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A 64-year-old male presents to your office with complaints of fatigue. He is generally well, takes no medications, and has not been to the physician in several years. His physical examination is unremarkable. You obtain a CBC: WBC 7,000/mm3, hemoglobin 7.4 g/dl, and platelet count 250,000/mm3. A peripheral blood smear reveals 2+ spherocytes. Haptoglobin is < 20 (low) and LDH is 300 IU/L (elevated). A direct antiglobulin test is positive.