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Microbiology, Fifth Edition
Microbiology, 5/e
Lansing M Prescott, Augustana College
Donald A Klein, Colorado State University
John P Harley, Eastern Kentucky University

Metabolism: The Use of Energy in Biosynthesis

Chapter Objectives

After reading this chapter you should be able to:
  • discuss the use of energy to construct more complex molecules and structures from smaller, simpler precursors
  • discuss the way that biosynthetic pathways are organized to conserve genetic storage space, biosynthetic raw materials, and energy
  • discuss the way that autotrophs use ATP and NADPH (or NADH) to reduce carbon dioxide and incorporate it into organic material
  • describe the assimilation of phosphorus, sulfur, and nitrogen
  • discuss the use of the TCA cycle as an amphibolic pathway and the need for anaplerotic reactions to maintain adequate levels of TCA cycle intermediates
  • discuss the synthesis of glucose (gluconeogenesis) and the synthesis of fatty acids
  • describe in general terms the synthesis of peptidoglycan and the construction of new cell walls