 |  Microbiology, 5/e Lansing M Prescott,
Augustana College
Donald A Klein,
Colorado State University
John P Harley,
Eastern Kentucky University
Metabolism: Energy, Enzymes, and Regulation
Chapter ObjectivesAfter reading this chapter you should be able to:
- discuss the first and second laws of thermodynamics and show how
they apply to biological systems
- discuss enthalpy, entropy, and free energy and their application
to biological reactions
- discuss the use of ATP as the energy currency of the cell and show
how it is used to couple energy-yielding exergonic reactions with energy-requiring
endergonic reactions
- discuss reduction potential and its relationship to exergonic and
endergonic processes
- describe the role of enzymes in the catalysis of biological reactions,
and discuss the ways in which enzymes are influenced by their environment
- discuss the need for metabolic regulation
- describe metabolic channeling
- describe how enzyme activity can be controlled by allosteric regulation
and covalent modification
- describe how feedback inhibition can be used to control the activity
of a metabolic pathway
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2002 McGraw-Hill Higher Education