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Multiple Choice Quiz
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1

Which of the following best describes the differences between macrophages and monocytes?
A)Macrophages are phagocytic and monocytes release substances such as histimine into the bloodstream.
B)Monocytes are phagocytic and macrophages release substances such as histimine into the bloodstream.
C)Macrophages attack bacterial antigens exclusively and monocytes attack viral antigens exclusively.
D)Macrophages are able to descriminate between bacterial and viral antigens but monocytes cannot.
E)They are the same type of cell but macrophages remain at one site and monocytes move through the bloodstream.
2

Natural killer cells attack
A)viruses only.
B)bacteria only.
C)parasitic protozoans only.
D)cancerous cells only.
E)infected body cells.
3

Killer cell:
A)initiates inflammation
B)mediates maturation of other cells in the same class
C)precurser to plasma cell
D)one type only attacks antibody-covered cells
4

B cell:
A)initiates inflammation
B)mediates maturation of other cells in the same class
C)precurser to plasma cell
D)one type only attacks antibody-covered cells
5

Inducer T cell:
A)initiates inflammation
B)mediates maturation of other cells in the same class
C)precurser to plasma cell
D)one type only attacks antibody-covered cells
6

Mast cell:
A)initiates inflammation
B)mediates maturation of other cells in the same class
C)precurser to plasma cell
D)one type only attacks antibody-covered cells
7

When helper T cells are activated they secrete _______ which stimulates proliferation of _______.
A)antibodies, B cells
B)antibodies, cytotoxic T cells
C)interleukin-2, cytotoxic T cells
D)interleukin-1, lymphokines
E)lymphokines, interleukin-2
8

IgA is found in bodily secretions such as breast milk and helps prevent pathogens from attaching to host tissues.
A)true
B)false
9

Memory T cells remain in the body for the rest of your life making you immune to any antigen you have encountered.
A)true
B)false
10

Joe Smith had the flu last year. This winter he "caught" the flu again. Why wasn't he immune the second time?
A)Memory cells produced in response to viral infections only last for a short period of time, usually only several weeks.
B)Joe obviously has a weak immune system.
C)Many viruses, such as influenza viruses are able to rapidly change their surface antigens thereby avoiding the previously produced memory cells.
D)Memory cells are only effective against bacteria and protozoans and are not able to recognize viral antigen.
E)None of the above explain why Joe caught the flu this year.
11

HIV is the highly contagious cause of acquired immunodeficiency syndrome.
A)true
B)false
12

HIV has an affinity for CD4+ cells and has little effect on the number of CD8+ cells in an infected individual.
A)true
B)false
13

Cells in the stratum corneum live there for about
A)8 hours.
B)a day.
C)a week.
D)a month.
E)2 to 3 months.
14

A membrane attack complex is
A)a group of macrophages that are attacking an invading bacterium or virus.
B)a group of activated complement molecules.
C)necessary for mast cells to release histamines.
D)found in viral infections only.
E)formed when B cells secrete antibody molecules.
15

Complement is activated by
A)exposure to proteins released by viral infected cells.
B)the lysis of neutrophils.
C)encounter with bacterial or fungal cell walls.
D)a decrease in vitamin C levels.
E)both a and d.
16

The redness and swelling that are associated with inflammation are due to
A)histamines.
B)the action of neutrophils.
C)chemical signals released from damaged cells.
D)the production of interleukins by macrophages.
E)waste products released by natural killer cells.
17

Macrophages
A)phagocytize invading microbes in the body.
B)produce interleukins.
C)identify foreign cells in cooperation with B and T cells.
D)examine the major histocompatibility proteins on the surface of the body's cells.
E)all of the above
18

Which of the following is the best description of the relationship between helper T cells and interleukin-1?
A)Helper T cells secrete interleukin-1 when they encounter a viral infected cell.
B)Interleukin-1 is a surface protein found on helper T cells.
C)Interleukin-1 is secreted by natural killer cells and it activates helper T cells.
D)Macrophages secrete interleukin-1, which then activates helper T cells.
E)Helper T cells secrete interleukin-1, which then activates macrophages.
19

Killer T cells help to eliminate infected body cells and cancer cells by
A)secreting antibodies to mark the cells for destruction.
B)phagocytosis.
C)fusing with them and secreting histamines that cause them to lyse.
D)puncturing the surface of the cell.
E)both a and d
20

The production of antibodies is initiated by the
A)release of interleukin-1.
B)release of interleukin-2.
C)release of histamines.
D)development of a fever.
E)killer T cells.
21

Mutations in the nef gene
A)render B cells ineffective.
B)result in increased allergies.
C)inhibit the release of histamines.
D)render HIV nonvirulent.
E)affect the ability of macrophages to release interleukin-1.
22

The symptoms of lupus are caused by
A)destruction of the myelin on motor nerves by the immune system.
B)an attack on the tissues of the joint by the immune system.
C)an attack on the connective tissue and kidneys by the immune system.
D)an attack on the thyroid by the immune system.
E)destruction of pancreas cells by the immune system.
23

Multiple sclerosis is caused by
A)destruction of the myelin on motor nerves by the immune system.
B)an attack on the tissues of the joint by the immune system.
C)an attack on the connective tissue and kidneys by the immune system.
D)an attack on the thyroid by the immune system.
E)destruction of pancreas cells by the immune system.
24

Graves disease is caused by
A)destruction of the myelin on motor nerves by the immune system.
B)an attack on the tissues of the joint by the immune system.
C)an attack on the connective tissue and kidneys by the immune system.
D)an attack on the thyroid by the immune system.
E)destruction of pancreas cells by the immune system.
25

HIV is transmitted by
A)unprotected sex.
B)protected sex.
C)exposure to contaminated needles.
D)all of the above
E)both a and c





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