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Multiple Choice Quiz
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1
Which of the following statements does NOT correctly describe antibodies?
A)Antibodies are secreted by plasma cells.
B)Antibodies protect against viruses by binding to them and presenting them to phagocytes.
C)Antibodies protect against viruses by binding to them and neutralizing them.
D)Antibodies activate complement.
E)Antibodies protect against viruses by binding to them and perforating them.
2
Which of the following statements regarding B cells is NOT true?
A)B cells can act as antigen-presenting cells.
B)B cells can secrete antibodies.
C)Activation of B cells requires class 1 MHC proteins
D)B cells are activated by cytokines.
E)B cells usually require T cells to be activated.
3
Antibodies against both type A and type B antigens are found in the plasma of a person whose blood type is ________.
A)type A.
B)type B.
C)type AB.
D)type O.
E)none of the above.
4
Which of the following people may suffer from a type of hemolytic anemia called "hemolytic disease of the newborn?"
A)an Rh+ fetus being carried by an Rh- mother.
B)an Rh- mother who is pregnant with an Rh+ fetus.
C)an Rh- fetus being carried by an Rh+ mother.
D)an Rh+ mother who is pregnant with an Rh- fetus.
E)an Rh- fetus who has an Rh+ father.
5
Chemotaxis
A)refers to the chemical attraction of erythrocytes to the site of inflammation.
B)is the mechanism by which neutrophils and monocytes migrate to the scene of microbial invasion or injury.
C)is responsible for the release of antibodies by lymphocytes.
D)A and B.
E)B and C.
6
Which of the following statements regarding phagocytes and phagocytosis is true?
A)Macrophages, monocytes and mast cells are phagocytes.
B)Contact of phagocytes with microbes stimulates the phagocytes to release chemicals that stimulate the inflammatory response.
C)Phagocytosis is stimulated by the presence of proteins called rhodopsins.
D)A and B.
E)A, B and C.
7
Which of the following statements regarding phagocytosis is true?
A)Macrophages are the only phagocytes in the tissues.
B)The microbe engulfed by the phagocyte is killed by lysosomal enzymes and hydrogen peroxide.
C)Phagocytosis is controlled by a negative feedback mechanism whereby phagocytes release chemicals that inhibit further phagocytosis.
D)The microbe engulfed by the phagocyte is killed by the membrane attack complex (MAC).
E)None of the above statements is true.
8
B and T cells are preprogrammed to recognize specific antigens.
A)True
B)False
9
The two broad categories of specific immune responses are antibody-mediated and humoral.
A)True
B)False
10
In cell-mediated immune responses, immune cells directly kill antigen-bearing cells.
A)True
B)False
11
Cytotoxic T cells destroy body cells by phagocytosis.
A)True
B)False
12
Interferons:
A)Are synthetic drugs developed to combat viruses
B)Are a type of antibody
C)Are a family of cytokines that specifically inhibit viral replication of specific viruses
D)Are a family of cytokines that non-specifically inhibit viral replication inside host cells
E)Are mainly secreted by lymphoid organ cells in response to viral infections
13
Which of the following is NOT correct about the NK cells?
A)They are a distinct class of lymphocytes
B)The are “natural killer” cells
C)They are functionally similar to cytotoxic T-cells
D)They attack cancer cells and virus infected cells
E)They are antigen specific and must recognize an antigen on a target cell before attacking it.
14
Which of the following is correct about lymphoid organs:
A)They occur as primary or secondary types
B)Lymph nodes and tonsils are examples of secondary lymphoid organs
C)Bone marrow and thymus are examples of primary lymphoid organs
D)Mature lymphocytes of the secondary lymphoid organs originate from bone marrow and thymus
E)All of the above are correct
15
Which of the following cells play major roles in rejection of a tissue graft (such as a kidney transplant from an unrelated donor)
A)Cytotoxic and Helper T- cells
B)Plasma cells
C)Macrophages
D)B-cells
E)None of the above
16
Which of the following is NOT true about the disease AIDS?
A)It is called Acquired Immune Deficiency Syndrome
B)It is a hereditary disorder
C)It is a viral disease caused by the HIV virus
D)It can be transmitted from mother to fetus
E)The infected individuals lose their reserves of T-cells, particularly the helper T-cells
17
Antibody molecules are immunoglobulin proteins that ________:
A)have a Y-shape structure with light chains and heavy chains
B)have conserved (constant) and variable ends in their protein structure
C)occur in a large variety in order to recognize and neutralize diverse infectious agents
D)are found at all ages, although not uniformly, so that some may be added during fetal life, others during lactation and still others during later adult life
E)All of the above are correct
18
Autoimmune diseases are caused by production of certain inappropriate antibodies which recognize body proteins as non-self (foreign) and attack them causing tissue destruction and diseases.
A)True
B)False
19
Antibiotics are naturally occurring or synthetic compounds which exclusively interfere with synthesis of proteins by the infectious microbes (such as bacteria).
A)True
B)False





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