Site MapHelpFeedbackStudy Outline
Study Outline
(See related pages)

  1. The Genetic Basis for Protein Synthesis
    1. Archibald Garrod proposed that some genes code for the production of a single enzyme
    2. Beadle and Tatum’s experiments with Neurospora led them to propose the one gene-one enzyme theory
    3. During translation, the genetic code within mRNA is used to make a polypeptide with a specific amino acid sequence
    4. Synthetic RNA helped to decipher the genetic code
    5. The use of RNA copolymers and the triplet binding assay also helped to crack the genetic code
    6. The amino acid sequences of polypeptides determine the structure and function of proteins
    7. Cellular proteins are primarily responsible for the characteristics of living cells and an organism’s traits
  2. Structure and Function of tRNA
    1. The function of a tRNA depends on the specificity between the amino acid it carries and its anticodon
    2. Translation depends on the recognition between the codon in mRNA and the anticodon in tRNA
    3. tRNAs share common structural features
    4. Aminoacyl-tRNA synthetases charge tRNAs by attaching an appropriate amino acid
    5. Mismatches that follow the wobble rule can occur at the third position in codon-anticodon pairing
  3. Ribosome Structure and Assembly
    1. Bacterial and eukaryotic ribosomes are assembled from rRNA and proteins
    2. Components of ribosomal subunits form functional sites for translation
  4. Stages of Translation
    1. The initiation stage involves the binding of mRNA and the initiator tRNA to the ribosomal subunits
    2. Polypeptide synthesis occurs during the elongation stage
    3. Termination occurs when a stop codon is reached in the mRNA
    4. A polypeptide chain has directionality from its amino terminus to its carboxyl terminus
    5. Bacterial translation can begin before transcription is completed
    6. The amino acid sequence of proteins contains sorting signals





To learn more about the book this website supports, please visit its Information Center.
(c)2005 McGraw-Hill Higher Education
Any use is subject to the Terms of Use and Privacy Policy.
McGraw-Hill Higher Education is one of the many fine businesses of The McGraw-Hill Companies.


GeneticsOnline Learning Center

Home > Chapter 13 > Study Outline