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Biology, 6/e
Author Dr. George B. Johnson, Washington University
Author Dr. Peter H. Raven, Missouri Botanical Gardens & Washington University
Contributor Dr. Susan Singer, Carleton College
Contributor Dr. Jonathan Losos, Washington University

Viruses

Multiple Choice Quiz

Please answer all questions



1

A lysogenic cycle involves
A)early lysis of the host cell
B)the ultimate formation of a prophage
C)lysis by the lambda lytic protein
D)a period of genome integration
2

The genetic alteration of a cell's genome is called
A)transformation
B)reverse transcription
C)genome conversion
D)invasion
3

The CD8+ cell antiviral factor (CAF) is used to
A)block the CCR5 receptor
B)disable the CXCR4 receptor
C)block replication of the HIV virus
D)mutate the CCR5 and CXCR4 receptors
4

The function of the drug AZT is to
A)disable reverse transcription
B)block production of envelope protein
C)block HIV replication
D)block capsid protein formation
5

Influenza subtypes differ in their
A)protein spikes
B)capsid composition
C)capsule composition
D)kinds of nucleic acids
6

When a bacteriophage is integrated into a cellular genome it is called a
A)virulent virus
B)lytic virus
C)prophage
D)transducing virus
E)microphage
7

The infectious substance of prions is
A)protein
B)glycophosphate
C)RNA
D)DNA
E)glycoprotein
8

Viruses are considered to be
A)non-living
B)primitive precursors of bacteria
C)a link between life and non-life
D)primitive organisms
E)very small bacteria
9

Each HIV particle possesses a glycoprotein called __________ on its surface
A)CD4
B)gp120
C)CXCR4
D)gp8
E)nef
10

The only structural pattern that has been found among isometric viruses is
A)icosahedral
B)spherical
C)helical
D)tetrahedral
E)capsular
11

__________ are small naked fragments of RNA that infect plant cells.
A)Prions
B)Nucleons
C)Prophages
D)Macrophages
E)Viroids
12

Viruses that cause lysis in host cells are called
A)temperate viruses
B)phagocytic viruses
C)prions
D)virulent viruses
E)infectious viruses
13

_________ is the virus causing fever blisters
A)Herpes simplex
B)Chlamydia
C)Epstein-Barr virus
D)Human papillomavirus
E)Lyme disease
14

Which of the following is not a viral disease?
A)mumps
B)measles
C)chicken pox
D)rubella
E)diphtheria
15

An example of an emerging virus is
A)Herpes
B)polio
C)rubella
D)CJD
E)Ebola
16

Copying the HIV virus' nucleic acid depends on
A)replicase
B)reverse transcriptase
C)transcriptase
D)reverse replicase
E)nucleases
17

Persons infected with HIV may not develop AIDS because the virus has the ________ gene.
A)CAF
B)gag
C)pol
D)nef
E)env
18

________ may prevent HIV replication by binding with the CD4 receptor.
A)gp120
B)CXCR4
C)Reverse transcriptase
D)CCR5
E)Chemokines
19

Typically, viruses form _______________ around their nucleic acid.
A)an envelope
B)a cell wall
C)a capsid
D)a cell membrane
E)a capsule
20

Viruses are most conveniently thought of as
A)lost chromosomes
B)the most primitive bacteria
C)particles of genomes
D)prions
E)escaped genomes
21

In AIDS patients, the virus homes in on the _______________ T cells.
A)CD1+
B)CD2+
C)CD3+
D)CD4+
E)CD5+
22

The viral enzyme, _________, causes the host cell to synthesize a double strand of DNA complementary to the viral RNA.
A)reverse transcriptase
B)chemokinase
C)virase
D)replicase
E)antiscriptase
23

The first virus to be purified was the
A)flu virus
B)tobacco mosaic virus
C)smallpox virus
D)polio virus
E)plague virus
24

When a virus kills the infected host cell in which it is replicating, the reproductive cycle is called a ________ cycle.
A)lysogenic
B)phagocytic
C)lytic
D)viroidal
E)endocytic
25

Of the viruses listed below, the most lethal is
A)influenza
B)Ebola
C)measles
D)herpes simplex
E)Epstein-Barr
26

Viruses have an overall structure that is
A)spherical
B)isometric
C)icosahedron
D)helical
E)all of the above
27

The basic structure of a virus contains:
A)a nucleic acid
B)a cell wall
C)a protein coat
D)both a and b
E)both a and c
28

Which of the following are not matched correctly:
A)virulent virus-lytic cycle
B)temperate virus-non-infecting virus
C)lysogenic virus-genome becomes part of host genome
D)lytic cycle-kills host cell
E)none of the above
29

Viruses are more closely related to chemical matter than to a living organism.
A)True
B)False
30

New strains of influenza continually arise because the virus mutates and recombines the gene encoding the protein that makes it resistant to antibodies.
A)True
B)False
31

The HIV virus uses the host cell's reverse transcriptase to manufacture DNA.
A)True
B)False
32

Some viruses enter the cell through endocytosis.
A)True
B)False
33

HIV binds to the human white blood cell receptor protein CD4.
A)True
B)False
34

HIV is a DNA virus.
A)True
B)False
35

Viruses and bacteria are the only infectious agents found in plants and animals.
A)True
B)False