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Microbiology, 5/e

Lansing M Prescott, Augustana College
Donald A Klein, Colorado State University
John P Harley, Eastern Kentucky University

The Viruses: Viruses of Eucaryotes

Multiple Choice Quiz

Choose the best answer


1	______ is probably the most important characteristic for classification of viruses in eucaryotes.
		A)	Host preference
		B)	Morphology
		C)	Physical nature of virion constituents
		D)	Chemical nature of virion constituents
		E)	Genetic relatedness


2	The _____ of the influenza-enveloped virus appear to be involved in attachment to the host cell receptor site.
		A)	Pili
		B)	Fimbriae
		C)	Flagellae
		D)	Hemagluttinin
		E)	Neuraminidase


3	Virulent and nonvirulent viruses may do any of the following but NOT
		A)	Inhibit host cell DNA synthesis
		B)	Inhibit host cell RNA synthesis
		C)	Inhibit host cell protein synthesis
		D)	Stimulate host cell macromolecule synthesis
		E)	Degrade host cell DNA


4	The hepadnaviruses such as hepatitis B virus are quite different from other DNA viruses with respect to genome replication. They replicate their DNA using
		A)	DNA-dependent DNA polymerase
		B)	Reverse transcriptase
		C)	Rnase H
		D)	RNA-dependent DNA polymerase
		E)	DNA ligase


5	Viral RNA is replicated in the host cell
		A)	Cytoplasmic matrix
		B)	Nucleus
		C)	Wall
		D)	Mitochondria
		E)	Lysozomes


6	Intracellular structures formed during many viral infections, called __________, which can directly disrupt cell structure.
		A)	Procaryotes
		B)	Chromosomal disruptions
		C)	Inclusion bodies
		D)	Cytocidal bodies
		E)	All of the above


7	With which of the following is virus always detectable after infections?
		A)	Hepatitis B virus
		B)	Herpes simplex virus
		C)	Varicella-zoster virus
		D)	Cytomegalovirus
		E)	Epstein-Barr virus


8	In cancer, the reversion of cells to a more primitive or less differnetiated state is called
		A)	Neoplasia
		B)	Anaplasia
		C)	Metastasis
		D)	Oncogenic
		E)	All of the above


9	Which of the following has been linked to cervical cancer?
		A)	Epstein-Barr virus
		B)	Human T-cell lymphotropic virus
		C)	Human immunodefficiency virus
		D)	Human papilloma virus
		E)	Human herpes virus 8


10	Which of the following has been linked to Kaposi's sarcoma?
		A)	Epstein-Barr virus
		B)	Human T-cell lymphotropic virus
		C)	Human immunodefficiency virus
		D)	Human papilloma virus
		E)	Human herpes virus 8


11	Which family has received most interest in their development as a biological control agent against insects?
		A)	Reoviridae
		B)	Baculoviridae
		C)	Iridoviridae
		D)	Poxviridae
		E)	Rhabdoviridae


12	Viroids are composed of
		A)	single-stranded DNA
		B)	double-stranded DNA
		C)	single-stranded RNA
		D)	double-stranded RNA
		E)	DNA and RNA


13	Which of the following is the agent associated with development of neurodegenrative disease in livestock and humans?
		A)	Viroids
		B)	virions
		C)	Virinos
		D)	Prions
		E)	Viruses


14	Eating meat from cattle with bovine spongiform encephalitis can cause a variant of _______ in humans.
		A)	Kuru
		B)	Fatal familial insomnia
		C)	Creutzfeldt-Jakob disease
		D)	Geistmann-Straussler-Scheinker syndrome
		E)	Alzheimer's disease


15	More support for the "protein only" hypothesis for prions has been supplied by studies on a prion found in
		A)	humans
		B)	cattle
		C)	sheep
		D)	yeast
		E)	bacteria

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