Multiple Choice Quiz


1	A compound synthesized by bacteria or fungi that destroys or inhibits the growth of other microbes is a/an
		A)	synthetic drug
		B)	antibiotic
		C)	antimicrobic drug
		D)	competitive inhibitor


2	Which statement is not an aim in the use of drugs in antimicrobial chemotherapy? The drug should:
		A)	have selective toxicity
		B)	be active even in high dilutions
		C)	be broken down and excreted rapidly
		D)	be microbicidal


3	Drugs that prevent the formation of the bacterial cell wall are
		A)	quinolones
		B)	beta-lactams
		C)	tetracyclines
		D)	aminoglycosides


4	Sulfonamide drugs initially disrupt which process?
		A)	folic acid synthesis
		B)	transcription
		C)	PABA synthesis
		D)	protein synthesis


5	Microbial resistance to drugs is acquired through
		A)	conjugation
		B)	transformation
		C)	transduction
		D)	all of these


6	R factors are ______ that contain a code for ______.
		A)	genes, replication
		B)	plasmids, drug resistance
		C)	transposons, interferon
		D)	plasmids, conjugation


7	When a patient's immune system becomes reactive to a drug, this is an example of
		A)	superinfection
		B)	drug resistance
		C)	allergy
		D)	toxicity


8	An antibiotic that disrupts the normal flora can cause
		A)	the teeth to turn brown
		B)	aplastic anemia
		C)	a superinfection
		D)	hepatotoxicity


9	Most antihelminth drugs function by
		A)	weakening the worms so they can be flushed out by the intestine
		B)	inhibiting worm metabolism
		C)	blocking the absorption of nutrients
		D)	inhibiting egg production


10	An example of an antiviral drug that can prevent a viral nucleic acid from being replicated is
		A)	azidothymidine
		B)	acyclovir
		C)	amantadine
		D)	both a and b


11	Which of the following effects do antiviral drugs not have?
		A)	killing extracellular viruses
		B)	stopping virus synthesis
		C)	inhibiting virus maturation
		D)	blocking virus receptors


12	Which of the following modes of action would be most selectively toxic?
		A)	interrupting ribosomal function
		B)	dissolving the cell membrane
		C)	preventing cell wall synthesis
		D)	inhibiting DNA replication


13	The MIC is the ______ of a drug that is required to inhibit growth of a microbe.
		A)	largest concentration
		B)	standard dose
		C)	smallest concentration
		D)	lowest dilution


14	An antimicrobic drug with a ______ therapeutic index is a better choice than one with a ______ therapeutic index.
		A)	low, high
		B)	high, low

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