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Multiple Choice Quiz
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1

The human genome project began as researchers mapped ____ and sites of cytogenetic abnormalities.
A)lods
B)RFLPs
C)PCRs
D)VNTRs
2

On which chromosome is the gene for Huntington disease located?
A)2
B)4
C)11
D)22
3

Which genetic map is the most detailed?
A)cytogenetic
B)linkage
C)physical
D)sequence
4

In the Sanger method of DNA sequencing, DNA synthesis ____ when a dideoxy base is encountered.
A)commences
B)continues
C)stops
D)increases
5

The first organism to have its genome sequenced was
A)Haemophilus influenzae.
B)Escherichia coli.
C)Mycoplasma genitalium.
D)Saccharomyces cerevisiae.
6

A gene can have different functions in different tissues at different times in development. True or false?
A)true
B)false
7

About ____ of the genes in Saccharomyces cerevisiae have counterparts among mammals.
A)1/4
B)1/3
C)1/2
D)2/3
8

Chromosomal and linkage maps are generated by
A)family data.
B)RFLP's.
C)positional cloning.
D)none of the above.
9

The Human Genome Project officially began in
A)1988.
B)1990.
C)1992.
D)1995.
10

Funding for the Human Genome Project comes from
A)the NIH.
B)the DOE.
C)the NIH and the DOE.
D)the NIH, the DOE and ELSI.
11

The Human Genome Project is limited to the study of humans. True or false?
A)true
B)false
12

With the advent of genomics, the concept of a gene is now clearly defined. True or false?
A)true
B)false
13

Genome information will affect your everyday life in many ways. True or false?
A)true
B)false
14

Of the two groups who worked on the first draft sequence of the human genome
A)Francis Collins and the International Consortium skipped the BAC stage.
B)Francis Collins led the effort by Celera Genomics.
C)Craig Venter's group shotgunned multiple copies of entire genomes into small pieces and used a computer program to assemble the overlaps into larger pieces.
D)All of the above are true.
15

The "Bermuda rules" stated that
A)researchers had to release new DNA sequences to the public database within 24 hours.
B)microarray technology could not be used for bioterrorism.
C)the human genome data would be posted on the internet.
D)GenBank would be in charge of organizing data regarding the human genome.





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