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nutrients  Chemical substances in food that contribute to health, many of which are essential parts of a diet. Nutrients nourish us by providing calories to fulfill energy needs, materials for building body parts, and factors to regulate necessary chemical processes in the body.
stroke  A decrease or loss in blood flow to the brain that results from a blood clot or other change in arteries in the brain. This in turn causes the death of brain tissue. Also called a cerebrovascular accident.
carbohydrate  A compound containing carbon, hydrogen, and oxygen atoms. Most are known as sugars, starches, and fibers. lipid A compound containing much carbon and hydrogen, little oxygen, and sometimes other atoms. Lipids dissolve in ether or benzene, but not in water, and include fats, oils, and cholesterol.
protein  Food and body components made of amino acids; proteins contain carbon, hydrogen, oxygen, nitrogen, and sometimes other atoms, in a specific configuration. Proteins contain the form of nitrogen most easily used by the human body.
vitamin  Compound needed in very small amounts in the diet to help regulate and support chemical reactions in the body.
mineral  Element used in the body to promote chemical reactions and to form body structures.
water  The universal solvent; chemically, H2O. The body is composed of about 60% water. Water (fluid) needs are about 9 (women) or 13 (men) cups per day; needs are greater if one exercises heavily.
atom  Smallest combining unit of an element, such as iron or calcium. Atoms consist of protons, neutrons, and electrons.
element  A substance that cannot be separated into simpler substances by chemical processes. Common elements in nutrition include carbon, oxygen, hydrogen, nitrogen, calcium, phosphorus, and iron.
glucose  A six-carbon monosaccharide that exits in a ring form; found as such in blood, and in table sugar bound to fructose; also known as dextrose, it is one of the simple sugars.
macronutrient  A nutrient needed in gram quantities in a diet.
micronutrient  A nutrient needed in milligram or microgram quantities in a diet.
cell  A minute structure; the living basis of plant and animal organization. In animals it is bounded by a cell membrane. Cells contain both genetic material and systems for synthesizing energy-yielding compounds. Cells have the ability to take up compounds from and excrete compounds into their surroundings.
bond  A linkage formed by the sharing of electrons, or attractions between two atoms.
fiber  Substances in plant foods that are not digested by the processes that take place in the human stomach or small intestine. These add bulk to feces. Fiber naturally found in foods is also called dietary fiber.
triglyceride  The major form of lipid in the body and in food. It is composed of three fatty acids bonded to glycerol, an alcohol.
fatty acid  Major part of most lipids; primarily composed of a chain of carbons flanked by hydrogen.
saturated fatty acid  A fatty acid containing no carbon-carbon double bonds.
unsaturated fatty acid  A fatty acid containing one or more carbon-carbon double bonds.
trans fatty acids  A form of an unsaturated fatty acid, usually a monounsaturated one when found in food, in which the hydrogens on both carbons forming that double bond lie on opposite sides of that bond, rather than on the same side (typical of fatty acids). Stick margarine, shortenings, and deep fat-fried foods in general are rich sources.
enzyme  A compound that speeds the rate of a chemical process but is not altered by the process. Almost all enzymes are proteins (some are made of genetic material).
amino acid  The building block for proteins containing a central carbon atom with nitrogen and other atoms attached.
chemical reaction  An interaction between two chemicals that changes both chemicals.
organic  Any substance that contains carbon atoms bonded to hydrogen atoms in the chemical structure.
inorganic  Any substance lacking carbon atoms bonded to hydrogen atoms in the chemical structure.
electrolytes  Substances that separate into ions in water and, in turn, are able to conduct an electrical current. These include sodium, chloride, and potassium.
solvent  A liquid substance in which other substances dissolve.
metabolism  Chemical processes in the body by which energy is provided in useful forms and vital activities are sustained.
genes  A specific segment on a chromosome. Genes provide the blueprints for the production of cell proteins.
alcohol  Ethyl alcohol or ethanol (CH3CH2OH).
compound  A group of different types of atoms bonded together in definite proportion.
ion  An atom with an unequal number of electrons and protons. Negative ions have more electrons than protons; positive ions have more protons than electrons.
hunger  The primarily physiological (internal) drive to find and eat food, mostly regulated by innate cues to eating.
appetite  The primarily psychological (external) influences that encourage us to find and eat food, often in the absence of obvious hunger.
satiety  State in which there is no longer a desire to eat; a feeling of satisfaction.
hypothalamus  A region at the base of the brain that contains cells that play a role in the regulation of hunger, respiration, body temperature, and other body functions.
gastrointestinal (GI) tract  The main sites in the body used for digestion and absorption of nutrients. It consists of the mouth, esophagus, stomach, small intestine, large intestine, rectum, and anus. Also called the digestive tract.
hormone  A compound secreted into the bloodstream by one type of cells that acts to control the function of another type of cells. For example, certain cells in the pancreas produce insulin, which in turn acts on muscle and other types of cells to promote uptake of nutrients from the blood.
endorphins  Natural body tranquilizers that may be involved in the feeding response.
ghrelin  A hormone made by the stomach that increases the desire to eat.
neuropeptide Y  A chemical substance made in the hypothalamus that stimulates food intake. The hormone leptin inhibits neuropeptide Y production.
leptin  A hormone made by adipose tissue in proportion to total fat stores in the body that influences long-term regulation of fat mass. Leptin also influences reproductive functions, as well as other body processes, such as release of the hormone insulin.
adipose tissue  A group of fat storing cells.
serotonin  A neurotransmitter synthesized from the amino acid tryptophan that affects mood (sense of calmness), behavior, and appetite, and induces sleep.
cholecystokinin (CCK)  A hormone that participates in enzyme release from the pancreas, bile release from the gallbladder, and hunger regulation.
hypotheses  "Educated guesses" by a scientist to explain a phenomenon.
pellagra  A deficiency disease characterized by inflammation of the skin, diarrhea, and eventual mental incapacity; results from an insufficient amount of the vitamin niacin in the diet.
experiments  Tests made to examine the validity of a hypothesis.
theory  An explanation for a phenomenon that has numerous lines of evidence to support it.
ulcer  Erosion of the tissue lining, usually in the stomach (gastric ulcer) or the upper small intestine (duodenal ulcer). As a group these are generally referred to as peptic ulcers.
microorganism  Bacteria, virus, or other organism that is invisible to the naked eye, some of which cause diseases. Also called microbes.
scurvy  The deficiency disease that results after a few weeks to months of consuming a diet that lacks vitamin C; pinpoint sites of bleeding on the skin are an early sign.
epidemiology  The study of how disease rates vary among different population groups.
infectious disease  Any disease caused by invasion of the body by microorganisms, such as bacteria, fungi, or viruses.
incidence  The number of new cases of a disease in a defined population over a specific period of time, such as 1 year.
animal model  Study of disease in animals that duplicates human disease. This can be used to understand more about human disease.
case-control study  Individuals who have the condition in question, such as lung cancer, are compared with individuals who do not have the condition.
double-blind study  An experimental design in which neither the participants nor the researchers are aware of each participant’s assignment (test or placebo) or the outcome of the study until it is completed. An independent third party holds the code and the data until the study has been completed.
control group  Participants in an experiment who are not given the treatment being tested.
placebo  Generally a fake medicine used to disguise the treatments given to the participants in an experiment.
peer-reviewed journal  A journal that publishes research only after two or three scientists who were not part of the study agree it was well conducted and the results are fairly represented. Thus, the research has been approved by peers of the research team.
megadose  Intake of a nutrient beyond estimates of needs or what would be found in a balanced diet; 3 to 10 times human needs is a starting point.
registered dietitian (R.D.)  A person who has completed a baccalaureate degree program approved by the American Dietetic Association, performed at least 900 hours of supervised professional practice, and passed a registration examination.







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