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solvent  A liquid substance in which other substances dissolve.
intracellular fluid  Fluid contained within a cell; it represents about two-thirds of all body fluid.
extracellular fluid  Fluid present outside the cells; represents about one-third of all body fluid.
electrolytes  Substances that separate into ions in water and, in turn, are able to conduct an electrical current. These include sodium, chloride, and potassium.
osmosis  The passage of a solvent such as water through a semipermeable membrane from a less concentrated compartment to a more concentrated compartment.
urea  Nitrogen-containing waste product of protein metabolism; major source of nitrogen in the urine.
amniotic fluid  Fluid contained in a sac within the uterus. This fluid surrounds and protects the fetus during development.
antidiuretic hormone  A hormone that is secreted by the pituitary gland and that acts on the kidneys to decrease water excretion.
aldosterone  A hormone produced by the adrenal glands that acts on the kidneys to conserve sodium (and therefore water).
cofactor  A mineral or other substance that binds to a specific region on a protein, such as an enzyme, and is necessary for the protein’s function.
major mineral  A mineral vital to health that is required in the diet in amounts greater than 100 milligrams per day.
trace mineral  A mineral vital to health that is required in the diet in amounts less than 100 milligrams per day.
bioavailability  The degree to which an ingested nutrient is absorbed and available to the body.
oxalic acid (oxalate)  An organic acid found in spinach, rhubarb, and other leafy green vegetables that can depress the absorption of certain minerals present in the food, such as calcium.
phytic acid (phytate)  A constituent of plant fibers that binds positive ions to its multiple phosphate groups.
diuretic  A substance that increases the flow of urine.
osteoporosis  Decreased bone mass related to the effects of aging, genetic background and poor diet in both genders, and hormonal changes at menopause in women.
tetany  A body condition marked by sharp contraction of muscles and failure to relax afterward; usually caused by abnormal calcium metabolism.
hemoglobin  The iron-containing part of the red blood cell that carries oxygen to the cells and some carbon dioxide away from the cells. The heme iron portion is also responsible for the red color of blood.
myoglobin  Iron-containing protein that binds oxygen in muscle tissue.
heme iron  Iron provided from animal tissues in the form of hemoglobin and myoglobin. Approximately 40% of the iron in meat is heme iron; it is readily absorbed.
nonheme iron  Iron provided from plant sources and animal tissues other than in the forms of hemoglobin and myoglobin. Nonheme iron is less efficiently absorbed than heme iron; absorption is closely dependent on body needs.
hematocrit  The percentage of blood that is made up of red blood cells.
anemia  Generally refers to a decreased oxygen-carrying capacity of the blood. This can be caused by many factors, such as iron deficiency or blood loss.
hemochromatosis  A disorder of iron metabolism characterized by increased iron absorption and deposition in the liver and heart tissue. This eventually poisons the cells in those organs.
goiter  An enlargement of the thyroid gland; this is often caused by insufficient iodide in the diet.
cretinism  The stunting of body growth and poor mental development in the offspring that results from inadequate maternal intake of iodide during pregnancy.
mottling  The discoloration or marking of the surface of teeth from fluorosis.
cortical bone  Dense, compact bone that comprises the outer surface and shafts of bone; also called compact bone.
trabecular bone  The spongy, inner matrix of bone, found primarily in the spine, pelvis, and ends of bones; also called spongy or cancellous bone.
bone mass  Total mineral substance (such as calcium or phosphorus) in a cross section of bone, generally expressed as grams per centimeter of length.
bone mineral density  Total mineral content of bone at a specific bone site divided by the width of the bone at that site, generally expressed as grams per cubic centimeter.
Dual energy X-ray absorptiometry (DEXA) bone scan  Method to measure bone density that uses small amounts of X-ray radiation. The ability of a bone to block the path of the radiation is used as a measure of bone density at that bone site.
bisphosphonates  Compounds primarily composed of carbon and phosphorus that bind to bone mineral and in turn reduce bone breakdown. Examples are alendronate (Fosamax) and risedronate (Actonel).







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