Choose the best answer

1			Who developed the concept of specific toxicity?
			A)	Jenner
			B)	Pasteur
			C)	Fleming
			D)	Watson
			E)	Ehrlich
2			Most antibiotics are isolated from
			A)	viruses.
			B)	fungi.
			C)	aquatic microorganisms.
			D)	soil microorganisms.
			E)	plants.
3			The larger the _______, the better the chemotherapeutic agent.
			A)	therapeutic index
			B)	toxic dose
			C)	therapeutic dose
			D)	selective toxicity
			E)	spectrum
4			Which of the following is NOT a semisynthetic chemotherapeutic agent?
			A)	Ampicillin
			B)	Carbenicillin
			C)	Methicillin
			D)	Penicillin
			E)	Sulfonamide
5			Which of the following tests is used to determine the minimal lethal concentration?
			A)	Broth dilution test
			B)	Agar dilution test
			C)	Dilution susceptibility tests
			D)	All of the above
			E)	None of the above
6			The most selective antibiotics are those that interfere with the synthesis of
			A)	bacterial DNA.
			B)	bacterial RNA.
			C)	bacterial cell walls.
			D)	bacterial plasma membrane.
			E)	bacterial pili.
7			Which of the following protein synthesis mechanisms may be affected by particular drugs?
			A)	Peptide bond formation
			B)	mRNA reading
			C)	mRNA translocation
			D)	Aminoacyl-tRNA binding
			E)	All of the above
8			A parenteral route of drug administration refers to
			A)	oral
			B)	nonoral
			C)	intravenously
			D)	intramuscularly
			E)	subcutaneously
9			Quinolones are
			A)	antimetabolites.
			B)	penicillin derivatives.
			C)	bacteristatic.
			D)	broad-spectrum.
			E)	narrow-spectrum.
10			Which antibiotic has a beta-lactam ring?
			A)	Cephalosporin
			B)	Penicillin
			C)	Tetracycline
			D)	Chloramphenicol
			E)	Streptomycin
11			Which of the following is used only in life-threatening situations when no other drug is adequate?
			A)	Cephalosporin
			B)	Penicillin
			C)	Tetracycline
			D)	Chloramphenicol
			E)	Streptomycin
12			Russian physicians are currently using which of the following to treat bacterial infections?
			A)	Other bacteria
			B)	Bacteriophage
			C)	Viruses
			D)	Fungi
			E)	Plant products