David Shier,
Washtenaw Community College Jackie L. Butler,
Grayson County College Ricki Lewis,
Contributing Editor to The Scientist
ISBN: 0072829532 Copyright year: 2007
Updates and Additions
Chapter 1 includes updated art on the internal environment, and discusses the role of cadavers in learning anatomy through the ages
Chapter 3 has updated coverage of stem and progenitor cells, and retains the best illustrations of basic stem cell biology to be found anywhere.
Chapter 4 has updated art supporting cellular metabolism and reordering of DNA replication to precede protein synthesis.
Chapter 5 has updated terminology, a new SEM of a mast cell, and a new Clinical Application on the extracelluar matrix and disease. The opening vignette compares traditional tissue atlases to the new molecular view of physiology using DNA microarrays to track gene expression.
Chapter 6 has a new vignette on the origin of hair, clarifies that subcutaneous is not a layer of skin, and has new small boxes on tatoos and botox.
Chapter 7 has a different vignette on clues from skeletons past and many updated art pieces.
Chapter 8 clarifies the interosseous membrane associated with syndesmosis, and rewords definitions of some movements.
Chapter 9 now discusses levers, moved from Chapter 7.
Chapter 10 clarifies membrane potentials and action potentials and includes five new figures to ease understanding of this difficult topic.
Chapter 12 has a new Clinical Application on treating pain.
Chapter 13 expands coverage of the hormonal control of appetite and eating, updates use of hormone replacement therapy in menopause and melatonin supplements, and the vignette discusses pancreatic islet transplants to treat diabetes.
Chapter 14 has a new vignette on universal precautions. The Clinical Application on King George III and Porphyria Variegata includes recent findings that arsenic exacerbated the genetic condition. The figure on the life cycle of a red blood cell is updated, coverage of LDL/HDL moved to chapter 18 (Nutrition and Metablism), and the origin of blood cells rewritten for clarity.
Chapter 15 is reorganized so that the summary figure of blood pressure, blood volume, ECG, and heart sounds is later in the chapter.Contractility and afterload are added to the cardiac output discussion, and the text and figure for capillary exchange are updated.
Chapter 16 adds complement to nonspecific defenses, and a “Reconnect” for the Elevated Body Temperature Clinical Application in Chapter 6 to the fever text section. A Science to Technology box introduces several children who have received gene therapies to treat inherited immune deficiencies. The Clinical Application on AIDS is updated.
Chapter 17 has a new vignette and updated Clinical Application on hepatitis, adds segmentation to mixing movements, and updates transport of lipids (more detail on LDL/HDL) in the small intestine.
Chapter 18 has a new vignette on Lance Armstrong's diet. Several food pyramids replace the dated, incorrect one, with additional discussion of vitamin and mineral toxicity, and consideration of infant nutrition in the Life Span section. New figures address BMR, scurvy, and hormonal control of weight.
Chapter 19 updates respiratory control, with modified art. The vignette updates reports on air quality and health consequences at the site of the terrorist attacks in New York City, and removes the disturbing photo.
Chapter 21 A new vignette on water intoxication highlights the dangers of drinking too much during a race, with a how-to on avoiding this condition.
Chapter 22 updates coverage of breast cancer and contraceptives. Figures much improved.
Chapter 23 has a new vignette on post-mortem sperm retrieval, a substantial new section on the end of life, and additional references to earlier chapters (with page numbers) to review developmental progression (infancy-adulthood).A new table provides practical information on assisted reproductive technologies.
Chapter 24 Thorough updating of impact of availability of human genome sequence on medical genetics, including discussion of anti-discrimination legislation in vignette. All the basics in a concise and clear presentation, with less emphasis on gene therapy in light of recent setbacks.
2007