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Short Answer Quiz
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1

Describe the inheritance of a simple Mendelian trait.
2

Describe a loss of function allele.
3

You are studying pituitary dwarfism in humans. You collect information from a large number of families where both parents are known to be heterozygous pituitary dwarves. (In each case, the grandparents were one dwarf and one person of normal stature). You notice that the ratio of affected to unaffected offspring is 2:1. What does this suggest?
4

Give an accurate definition of an essential gene.
5

Give two examples of traits for which there are more than two alleles.
6

Differentiate between codominance and incomplete dominance at the molecular level.
7

What is the proposed mechanism that causes temperature sensitive alleles?
8

How might a temperature sensitive lethal mutation be useful for a geneticist?
9

You decide to test the hypothesis that the Himalayan coat color in rabbits is due to a temperature sensitive allele. You shave the back of the rabbit and strap a cold pack on the naked region. What prediction does your hypothesis allow you to make about the color of the newly grown hair?
10

Explain why the IA allele at the ABO blood type locus can be considered both dominant and codominant.
11

Differentiate between overdominance and heterosis.
12

What is the predicted phenotypic ratio for the offspring of a cross between a chinchilla rabbit heterozygous for the himalayan allele and a himalayan rabbit heterozygous for the albino allele?
13

What is the predicted phenotypic ratio for the offspring of a cross between a chinchilla rabbit heterozygous for the albino allele and a himalayan rabbit heterozygous for the albino allele?
14

What is meant by a gene having a gene dosage effect?
15

Describe the three suggested molecular mechanisms of overdominance.
16

What is the major mechanism used to explain sex-limited inheritance?





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