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| Gilbert, Walter. February 9, 1978. Why genes in pieces? Nature, vol. 271, p. 501. A classic and insightful look at the enigma of introns. Ingram, V. M. 1957. Gene mutations in human hemoglobin: The chemical difference between normal and sickle cell hemoglobin. Nature, vol. 180, p. 1326. This classic paper explains the molecular basis for sickle cell disease. International Human Genome Mapping Consortium. February 15, 2001. A physical map of the human genome. Nature, vol. 409, p. 934. The public first-draft human genome sequence. Other articles in this issue discuss specific chromosomes. Kay, Lily E. 2001. Who Wrote the Book of Life? Stanford, CA: Stanford University Press. The story of how a group of mostly physicists-turned-biologists deciphered the genetic code, in the 1960s. Lewis, Ricki. March 18, 2002. Pufferfish genomes probe human genes. The Scientist, vol. 16, no. 6, p. 22. Researchers are using clues in two pufferfish genomes to identify human genes. Lewis, Ricki. January 5, 1998. Comparative genomics reveals the interrelatedness of life. The Scientist, vol. 12, no. 1, p. 5. Probing genomes shows that species are more alike than different. Lewis, Ricki, and Barry Palevitz. June 11, 2001. Genome economy. The Scientist, vol. 15, no. 12, p. 19. The article that forms the basis for section 10.3 of this book shows how the genome specifies many proteins with few genes. Venter, J. C., et al. February 16, 2001. The sequence of the human genome. Science, vol. 291, pp. 1304-1351. Celera Genomics obtained the first draft human genome sequence using an approach that many thought would not work. |