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1 | | Jaundice reflects an accumulation of ______________ in the blood. (p. 693) |
| | A) | iron |
| | B) | bile |
| | C) | heme |
| | D) | urochrome |
| | E) | bilirubin |
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2 | | The gene for sickle cell arose as a defense for what disease? (p. 695) |
| | A) | malaria |
| | B) | thalassemia |
| | C) | iron-deficiency anemia |
| | D) | erythroblastosis fetalis |
| | E) | polycythemia |
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3 | | These cells secrete histamine and do not appear to have any phagocytic capabilities (table 18.8-pp. 701-702) |
| | A) | eosinophils |
| | B) | basophils |
| | C) | neutrophils |
| | D) | lymphocytes |
| | E) | macrophages |
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4 | | Platelets do all of the following except: (pp. 704-705) |
| | A) | they help form blood clots |
| | B) | they help a blood vessel repair itself |
| | C) | they secrete clotting factors |
| | D) | they carry oxygen to injured areas of tissue |
| | E) | they secrete vasoconstrictors which promote vascular spasms |
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5 | | Monocytes differentiate into macrophages before they phagocytize material. (pp. 689, 702-703) |
| | A) | True |
| | B) | False |
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6 | | Which of the following organs serves as a major storehouse for iron? (p. 688) |
| | A) | liver |
| | B) | kidney |
| | C) | bone |
| | D) | thymus |
| | E) | skeletal muscle |
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7 | | Which of the following statements about blood is false? |
| | A) | Most adults have 4 to 6 liters of blood. |
| | B) | An excess of plasma protein causes the blood to flow too sluggishly. |
| | C) | As the protein content of the blood plasma drops, so does its osmolarity. |
| | D) | The fluid remaining after blood clots is the same as blood plasma. |
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8 | | Which of the following organs produces all the plasma proteins except the gamma globulins, which come from plasma cells? |
| | A) | small intestine |
| | B) | kidney |
| | C) | liver |
| | D) | spleen |
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9 | | Lymphocytes multiply continuously and give rise to all of the cellular elements of blood. |
| | A) | True |
| | B) | False |
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10 | | Which cell stage in the formation of erythrocytes has lost its nucleus and yet retains a fine network of endoplasmic reticulum? |
| | A) | reticulocyte |
| | B) | erythroblast |
| | C) | proerythroblast |
| | D) | normoblast |
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11 | | Monocytes leave the bone marrow to live for years in the tissues as macrophages. |
| | A) | True |
| | B) | False |
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12 | | Which of the following cell types releases the tiny cell fragments that we call platelets from the edges of its cytoplasm? |
| | A) | myeloblast |
| | B) | megakaryocyte |
| | C) | erythroblast |
| | D) | hemocytoblast |
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13 | | Each hemoglobin molecule can carry up to how many oxygen molecules bound to its heme group? |
| | A) | 1 |
| | B) | 2 |
| | C) | 4 |
| | D) | 6 |
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14 | | Which of the following statements is true about a male with a normal amount of red blood cells? |
| | A) | His hematocrit reading is 43%. |
| | B) | His hemoglobin concentration is 10g/dL. |
| | C) | His red blood cell count is 3.6 million/microliter. |
| | D) | His blood is 69% plasma. |
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15 | | Anemia can be caused by all of the following except |
| | A) | nutritional deficiency of vitamin B12 or iron. |
| | B) | failure of gastric production of intrinsic factor. |
| | C) | kidney failure. |
| | D) | hypoxemia from smoking or air pollution. |
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16 | | People with sickle-cell trait are resistant to the malaria parasite. |
| | A) | True |
| | B) | False |
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17 | | Antibody B is present in the blood plasma of individuals with which blood types? |
| | A) | types A and O |
| | B) | type B |
| | C) | types B and A |
| | D) | types B and O |
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18 | | Neither O+ nor O- individual normally have antibody D (anti-D agglutinins) in their plasma. |
| | A) | True |
| | B) | False |
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19 | | Which of the following is incorrectly matched? |
| | A) | lymphocytes:dark purple cytoplasmic granules |
| | B) | eosinophils:red cytoplasmic granules |
| | C) | neutrophils:nucleus divided into two or five lobes |
| | D) | monocytes:large blood cells with round or kidney-shaped nucleus |
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20 | | Which of the following is true? |
| | A) | A vascular spasm is a short-lived constriction of a leaking vessel. |
| | B) | Platelet plugs are formed when exposed collagen fibers in a broken blood vessel come in contact with platelets. |
| | C) | Coagulation is the formation of fibrin threads from plasma fibrinogen. |
| | D) | All of the above are true. |
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21 | | Coagulation is initiated by tissue thromboplastin released from damaged tissues or by platelets releasing clotting factor XII within an intact blood vessel. |
| | A) | True |
| | B) | False |
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22 | | Aspirin suppresses the formation of thrombosis and helps prevent heart attacks. |
| | A) | True |
| | B) | False |
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23 | | Which of the following is an example of a clot-dissolving drug used to dissolve clots in coronary arteries? |
| | A) | coumadin |
| | B) | streptokinase |
| | C) | thrombocytopenia |
| | D) | antihemophilic factor |
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24 | | Because this blood protein is so abundant, it contributes greatly to osmolarity and viscosity: |
| | A) | globulin |
| | B) | antibody |
| | C) | fibrinogen |
| | D) | albumin |
| | E) | erythropoetin |
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25 | | If a person moved from the sea shore to a very high mountain, where the air pressure is reduced, what might happen to the hematocrit readings? |
| | A) | red blood cells increase |
| | B) | white blood cells increase |
| | C) | red blood cell count declines |
| | D) | white blood cell numbers fall |
| | E) | plasma increases |
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26 | | This hormone, produced by the kidneys, stimulates red blood cell production: |
| | A) | transferrin |
| | B) | erythropoetin |
| | C) | interleukin |
| | D) | colony-stimulating factor |
| | E) | thrombopoietin |
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27 | | These cells produce platelets: |
| | A) | myeloblasts |
| | B) | reticulocytes |
| | C) | lymphoblasts |
| | D) | monocytes |
| | E) | megakaryocytes |
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28 | | During hemolysis, heme is produced. The heme is first converted to: |
| | A) | bilirubin |
| | B) | hemoglobin |
| | C) | biliverdin |
| | D) | urobilinogen |
| | E) | bile |
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29 | | A person with type A blood has: |
| | A) | anti-B agglutinin |
| | B) | anti-A agglutinin |
| | C) | anti-B agglutinin and anti-A agglutinin |
| | D) | A and B agglutinogens |
| | E) | B agglutinogen |
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30 | | If an Rh negative mother has a second fetus with Rh positive blood, then: |
| | A) | the mother should be transfused |
| | B) | the mother will begin to make Rh positive blood cells |
| | C) | anti-Rh antibodies may attack fetal cells |
| | D) | the mother should avoid RhoGAM |
| | E) | the mother needs phototherapy |
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31 | | A differential white blood cell count shows an abnormally high count of mature neutrophils. This is a sign of: |
| | A) | myelocytic leukemia |
| | B) | lymphocytic leukemia |
| | C) | bacterial infection |
| | D) | parasitic infestation |
| | E) | heart attack |
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32 | | EDTA binds with this metallic ion, a required cofactor in many steps in the blood clotting process: |
| | A) | iron |
| | B) | sodium |
| | C) | chloride |
| | D) | calcium |
| | E) | potassium |
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33 | | The final product in the blood clotting process is: |
| | A) | fibrin |
| | B) | thrombin |
| | C) | thromboplastin |
| | D) | factor X |
| | E) | platelets |
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34 | | This genetic X-linked disorder results in a lack of factor VIII: |
| | A) | von Wittebrand disease |
| | B) | hemophilia A |
| | C) | hemophilia B |
| | D) | thrombocytopenia |
| | E) | heparin |
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