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Prenatal period (pree-NAY-tul)  The time from conception to birth.
Hormones  Chemical substances secreted by the endocrine glands into the bloodstream.
Testosterone  A hormone secreted by the testes in the male (and also present at lower levels in the female).
Androgens  The group of male sex hormones, one of which is testosterone.
Estrogens (ESS-troh-jens)  The group of female sex hormones.
Progesterone (pro-JES-tur-ohn)  A female sex hormone secreted by the ovaries.
Pituitary gland (pih-TOO-ih-tair-ee)  A small endocrine gland located on the lower side of the brain below the hypothalamus; the pituitary is important in regulating levels of sex hormones.
Hypothalamus (hy-poh-THAL-ah-mus)  A small region of the brain that is important in regulating many body functions, including the functioning of the sex hormones.
Follicle-stimulating hormone (FSH)  A hormone secreted by the pituitary; it stimulates follicle development in females and sperm production in males.
Luteinizing hormone (LH)  A hormone secreted by the pituitary; it regulates estrogen secretion and ovum development in the female and testosterone production in the male.
GnRH (gonadotropin-releasing hormone)  A hormone secreted by the hypothalamus that regulates the pituitary's secretion of gonad-stimulating hormones.
HPG axis  Hypothalamus-pituitary-gonad axis, the negative feedback loop that regulates sex-hormone production.
Inhibin  A substance secreted by the testes and ovaries which regulates FSH levels.
SRY  Stands for sex-determining region, Y chromosome.
Müllerian ducts  Ducts found in both male and female fetuses; in males they degenerate and in females they develop into the fallopian tubes, the uterus, and the upper part of the vagina.
Wolffian ducts  Ducts found in both male and female fetuses; in females they degenerate and in males they develop into the epididymis, the vas deferens, and the ejaculatory duct
Cryptorchidism  Undescended testes; the condition in which the testes do not descend to the scrotum as they should during prenatal development.
Homologous organs (huh-MOLL-uh-gus)  Organs in the male and female that develop from the same embryonic tissue.
Analogous organs (an-AL-uh-gus)  Organs in the male and female that have similar functions.
Intersex  An individual who has a mixture of male and female reproductive structures, so that it is not clear at birth whether the individual is a male or a female. Also called a pseudohermaphrodite.
Congenital adrenal hyperplasia (CAH)  A condition in which a genetic female produces abnormal levels of androgens prenatally and therefore has male-appearing genitals at birth.
Androgen-insensitivity syndrome (AIS)  A genetic condition in which the body is unresponsive to androgens so that a genetic male may be born with a female-appearing body.
Puberty  The time during which there is sudden enlargement and maturation of the gonads, other genitalia, and secondary sex characteristics, so that the individual becomes capable of reproduction.
Menarche (MEN-ar-key)  First menstruation.
Leptin  A protein produced in the body that is related to the onset of puberty.
Adrenal glands (uh-DREE-nul)  Endocrine glands located just above the kidneys; in the female they are the major producers of androgens.
Adrenarche (AD-ren-ar-key)  A time of increased secretion of adrenal androgens, usually just before age eight.







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