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Biology, 6/e
Author Dr. George B. Johnson, Washington University
Author Dr. Peter H. Raven, Missouri Botanical Gardens & Washington University
Contributor Dr. Susan Singer, Carleton College
Contributor Dr. Jonathan Losos, Washington University
The Immune System

Multiple Choice Quiz

Please answer all questions



1

Which of the following actually kills invading microbes?
A)lysozymes
B)stomach acid
C)intestinal enzymes
D)all of the above
2

The inflammatory response includes all of the following except
A)vessel constriction
B)temperature increase
C)increased blood flow
D)phagocyte attack
3

The secretion of antibodies by lymphocyte B cells provides
A)cell-mediated immunity
B)passive immunity
C)humoral immunity
D)permanent immunity
4

The immunoglobulin found in a mother's milk is
A)IgM
B)IgA
C)IgE
D)IgG
5

Erythroblastosis fetalis can result if
A)the Rh+ mother is sensitized to the Rh- antigen and the baby is Rh-
B)the Rh- mother is sensitized to the Rh+ antigen and the baby is Rh-
C)the Rh- mother is sensitized to the Rh+ antigen and the baby is Rh+
D)the Rh+ mother is sensitized to the Rh- antigen and the baby is Rh+
6

AIDS is such a deadly disease because the AIDS virus attacks and destroys
A)CD4+ T cells
B)B cells
C)CD8+ T cells
D)macrophages
E)memory cells
7

Which of the following statements about AIDS is true?
A)The disease is highly infectious.
B)The fatality rate is low if the disease is detected in its early stages.
C)Most people who get AIDS die of pneumonia.
D)all of the above
E)none of the above
8

Which of the following are autoimmune diseases
A)heart disease
B)Hashimoto's thyroiditis
C)erythroblastosis fetalis
D)systemic lupus erythematosus
E)both b and d
9

The proteins secreted by plasma cells are called
A)MHC
B)complement
C)antigens
D)cytokines
E)antibodies
10

A person with anti-A and anti-B antibodies in their blood has what blood type?
A)type A
B)type B
C)type AB
D)type O
11

Precursors of macrophages are called
A)T cells
B)killer cells
C)B cells
D)plasma cells
E)monocytes
12

The immune response is terminated or decreased by
A)suppressor B cells
B)suppressor T cells
C)both of the above
D)none of the above; the immune response can only be stimulated, not terminated
13

Which type of T cell lyses cells that have been infected with viruses?
A)inducer T cells
B)helper T cells
C)cytotoxic T cells
D)suppressor T cells
E)none of the above
14

When a B cell encounters antigen to which it is targeted, it divides rapidly and produces
A)more antigen
B)plasma cells
C)T cells
D)killer cells
E)interferons
15

All of the following cells are phagocytic except for
A)basophils
B)neutrophils
C)lymphocytes
D)eosinophils
E)all of the above are phagocytic
16

Your body has millions of different antibodies for detecting millions of different antigens because
A)you have millions of different antibody genes
B)antibody genes undergo somatic rearrangement and somatic mutation
C)antibody genes undergo antigen shifting
D)all of the above
E)none of the above
17

Helper T cells and inducer T cells are also called _______________ cells because of the coreceptor they both have.
A)CD4+ T
B)CD8+ T
C)CD16+ T
D)CD12+ T
18

Which type of surface marker is present on every nucleated cell in your body?
A)B receptor
B)T receptor
C)MHC-I
D)MHC-II
E)all of the above
19

MHC proteins are also called
A)ABC
B)HIV
C)Ig
D)HLA
E)hybridomas
20

Activated helper T cells release regulatory molecules called
A)histamines
B)antibodies
C)pus
D)lymphokines
E)complement
21

Memory cells
A)produce cyclosporine
B)are responsible for passive immunity
C)prevent an animal from encountering certain antigens
D)provide an accelerated immune response upon second exposure to a particular antigen
E)all of the above
22

What holds together the four polypeptide chains of an antibody?
A)disulfide bonds
B)light chains
C)heavy chains
D)complement proteins
E)MHC proteins
23

Of the five classes of antibody heavy chains, which one's function is still partially unclear?
A)IgE
B)IgM
C)IgG
D)IgA
E)IgD
24

Diseases in which a person's immune system attacks the person's own normal tissue are called
A)secondary immune diseases
B)autoimmune diseases
C)antigen shifting diseases
D)primary immune diseases
E)clonal selection diseases
25

The cells that you see when you look at your skin were produced in the
A)dermis
B)psoriasis layer
C)subcutaneous tissue
D)stratum basale
E)stratum corneum
26

Which of the following cells participate in nonspecific defense responses when your body is invaded by microbes?
A)natural killer cells
B)macrophages
C)neutrophils
D)all of the above
E)none of the above
27

Cytotoxic T cells are called into action by the:
A)presence of interleukin-1
B)presence of interleukin-2
C)presence of neutrophils
D)decrease in the number of B cells
E)decrease in the number of antibodies
28

Complement and antibody are similar in that both:
A)are produced by mast cells.
B)may make bacteria more attractive to phagocytes.
C)have two identical antigen-binding sites.
D)are activated in an inflammatory cascade.
29

The AIDS virus:
A)is also know as HTLV.
B)has a high affinity for CD8 bearing T cells.
C)may become dormant in cells.
D)is a DNA virus.
30

Hypersensitivity reactions:
A)are sometimes mediated by IgE.
B)may involve immune complexes.
C)may involve complement, histamine, neutrophils or IgG.
D)all of the above.
31

Which cell is correctly matched with its secretion or function?
A)T-lymphocyte -- IL-1
B)mast cells -- histamine
C)macrophage -- IgA
D)eosinophil -- clotting
32

All of the following are part of our antigen specific defense mechanisms except:
A)acute inflammation.
B)lymphocytes.
C)antibody production.
D)macrophages.
33

Echinoderms have immune systems similar to bony fish in that they possess T and B lymphocytes
A)True
B)False
34

Immunoglobulins have two light chains and two heavy chains.
A)True
B)False
35

IgE is an interleukin involved in allergies.
A)True
B)False
36

T cytotoxic cells produce cytokinins which cause the lysis of other target cells.
A)True
B)False
37

Hemolytic disease of the newborn typically results from immunization of an RH- mother with Rh+ blood from her first pregnancy, the antibodies reacting against the fetus in a later pregnancy.
A)True
B)False








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