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1 |  |  If ATP synthase is enzymatically neutralized within a cell, which of the following consequences would be the most logical outcome? |
|  | A) | Negative feedback will be decreased, causing faster ATP production. |
|  | B) | The electron transport chain will slow down. |
|  | C) | The cell will have no mechanism to make ATP and will die. |
|  | D) | Phosphylation of ADP will decrease. |
|  | E) | All of the above will occur. |
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2 |  |  For one molecule of glucose, what is the maximum number of ATP molecules created directly from the Krebs cycle? |
|  | A) | 1 |
|  | B) | 2 |
|  | C) | 3 |
|  | D) | 4 |
|  | E) | 5 |
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3 |  |  What is the name of the mechanism by which pyruvate dehydrogenase is inhibited by the end-product of the biochemical pathway? |
|  | A) | Anabolism |
|  | B) | Catabolism |
|  | C) | Regulation |
|  | D) | Negative inhibition |
|  | E) | Anti-phosphorylation |
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4 |  |  During yeast fermentation, CO2 is produced, but animal cells do not produce CO2. What is the difference in their fermentation strategies? |
|  | A) | Yeast fermentation creates ethanol. |
|  | B) | Animal cells create ATP and ethanol. |
|  | C) | Animal cells do not undergo fermentation. |
|  | D) | Yeast cells ferment pyruvate to lactic acid. |
|  | E) | There is no difference in their fermentation pathways. |
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5 |  |  Which of the following argues most strongly for glycolysis as one of the most primitive biochemical pathway? |
|  | A) | It does not require oxygen in order to function. |
|  | B) | It occurs in the cytoplasm of cells. |
|  | C) | It is exergonic, and therefore obeys the laws of thermodynamics which are fundamental to chemistry and physics. |
|  | D) | This biochemical pathway has been retained by all living organisms. |
|  | E) | There is no evidence that glycolysis is primitive |
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6 |  |  Cellular respiration is |
|  | A) | the utilization of oxygen in a cell. |
|  | B) | the oxidation of organic compounds to extract energy from chemical bonds. |
|  | C) | production of ATP in a cell. |
|  | D) | the conversion of the energy of sunlight to chemical energy. |
|  | E) | reduction of NADH to drive chemical reactions in a cell. |
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7 |  |  Because it has 6 carbons, glucose can power 6 cycles ("turns") of the Krebs cycle |
|  | A) | True |
|  | B) | False |
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8 |  |  Which of the following statements is false? |
|  | A) | Some ATP is consumed in glycolysis. |
|  | B) | The end product of glycolysis is lactic acid or ethanol. |
|  | C) | Some ATP is created through substrate-level phosphorylation. |
|  | D) | Overall, glycolysis releases energy and is thus termed exergonic. |
|  | E) | All of the above statements are true. |
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9 |  |  Where in a eukaryotic cell does pyruvate oxidation occur? |
|  | A) | In the mitochondrion. |
|  | B) | In the electron transport chain. |
|  | C) | In the cytoplasm, just like in prokaryotes. |
|  | D) | Anywhere in the cell, provided pyruvate dehydrogenase is present. |
|  | E) | In ribosomes. |
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10 |  |  The Krebs cycle is responsible for making most of the cell's ATP. |
|  | A) | True |
|  | B) | False |
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11 |  |  Which of the following is most directly responsible for creation of ATP at the mitochondrial inner membrane? |
|  | A) | NADH |
|  | B) | A proton gradient |
|  | C) | FADH2 |
|  | D) | Movement of electrons along the membrane itself |
|  | E) | The activity of NADH dehydrogenase |
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12 |  |  Which of these is one of the correct reasons that less than the theoretical amount of ATP (36-38) is actually created during aerobic respiration? |
|  | A) | Because of the efficiency of chemiosmosis, the result is actually much higher. |
|  | B) | FADH2 actually consumes some ATP. |
|  | C) | The cell membrane is somewhat leaky to electrons. |
|  | D) | The proton gradient can facilitate other tasks besides ATP synthesis. |
|  | E) | You have to add in ATP produced during glycolysis, which has nothing to do with oxidation. |
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13 |  |  True or False: The purpose of fermentation is to make ethanol. |
|  | A) | True |
|  | B) | False |
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14 |  |  What process must occur to allow amino acids to be catabolized for energy? |
|  | A) | Deamination |
|  | B) | Depurination |
|  | C) | Dephosphorylation |
|  | D) | Dehydration |
|  | E) | Deoxygenation |
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15 |  |  Primitive prokaryotes probably used H2S instead of water as a source of electrons. What would have been released into the environment as photosynthesis occurred? |
|  | A) | Gaseous hydrogen |
|  | B) | Liquid hydrogen |
|  | C) | Water |
|  | D) | HS |
|  | E) | Sulfur |
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