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Core Concepts in Health Cover Image
Core Concepts in Health, 9/e
Paul M. Insel, Stanford University School of Medicine
Walton T. Roth, Stanford University School of Medicine

Sexually Transmitted Diseases


acquired immunodeficiency syndrome (AIDS)  A generally fatal, incurable, sexually transmitted viral disease.
human immunodeficiency virus (HIV)  The virus that causes HIV infection and AIDS.
sexually transmitted disease (STD)  A disease that can be transmitted by sexual contact; some STDs can also be transmitted by other means.
HIV infection  A chronic, progressive disease that damages the immune system.
CD4 T cell  A type of white blood cell that helps coordinate the activity of the immune system; the primary target for HIV infection. A decrease in the number of these cells correlates with the risk and severity of HIV-related illness.
asymptomatic  Showing no signs or symptoms of a disease.
hemophilia  A hereditary blood disease in which blood fails to clot and abnormal bleeding occurs, requiring transfusions of blood products with a specific factor to aid coagulation.
HIV RNA assay  A test used to determine the amount of HIV in the blood (the "viral load").
Pneumocystis carinii pneumonia  A protozoal infection that is common in people infected with HIV.
Kaposi's sarcoma  A form of cancer characterized by purple or brownish lesions that are generally painless and occur anywhere on the skin; usually appears in men infected with HIV.
HIV antibody test  A blood test to determine whether a person has been infected by HIV; becomes positive within weeks or months of exposure.
ELISA (enzyme-linked immunosorbent assay)  A blood test that detects the presence of antibodies to HIV.
Western blot  A blood test that detects the presence of HIV antibodies; a more accurate and more expensive test, and used to confirm positive results from an ELISA test.
antibody  A protein produced in the blood in response to a foreign substance to which it binds.
HIV-positive  A diagnosis resulting from the presence of HIV in the bloodstream; also referred to as seropositive.
reverse transcriptase inhibitor  An antiviral drug used to treat HIV infection that works by inhibiting reverse transcriptase, the enzyme that converts viral RNA to DNA.
protease inhibitor  A drug that inhibits the action of any of the protein-splitting enzymes known as proteases. Protease inhibitors have been developed to block the action of HIV protease and thus prevent the replication of HIV.
seroconversion  The appearance of antibodies to HIV in the blood of an infected person; usually occurs 1-6 months after infection.
*chlamydia  An STD transmitted by the pathogenic bacterium Chlamydia trachomatis.
epididymitis  An inflammation of the small body of ducts that rests on the testes.
urethritis  Inflammation of the tube that carries urine from the bladder to the outside opening.
gonorrhea  A sexually transmitted bacterial infection that usually affects mucous membranes.
gonococcal conjunctivitis  An inflammation of the mucous membrane lining of the eyelids, caused by the gonococcus bacterium.
pelvic inflammatory disease (PID)  An infection that progresses from the vagina and cervix to the uterus, oviducts, and pelvic cavity.
genital warts  A sexually transmitted viral infection characterized by growths on the genitals; also called genital HPV infection.
human papillomavirus (HPV)  The pathogen that causes human warts, including genital warts.
genital herpes  A sexually transmitted infection caused by the herpes simplex virus.
hepatitis  Inflammation of the liver, which can be caused by infection, drugs, or toxins; some forms of infectious hepatitis can be transmitted sexually.
syphilis  A sexually transmitted bacterial infection caused by the spirochete Treponema pallidum.
chancre  The sore produced by syphilis in its earliest stage.
trichomoniasis  A protozoal infection caused by Trichomonas vaginalis, transmitted sexually and externally.
bacterial vaginosis (BV)  A condition linked to sexual activity; caused by an overgrowth of certain bacteria inhabiting the vagina.
chancroid  A sexually transmitted bacterial infection caused by Haemophilus ducreyi.
pubic lice  Parasites that infest the hair of the pubic region, commonly called crabs.
scabies  A contagious skin disease caused by a type of parasitic mite.
opportunistic infection  An infection caused when organisms take the opportunity presented by a primary (initial) infection to multiply and cause a secondary infection.
microbicide  An agent that destroys microorganisms; also known as an antiseptic.