Which of the following is not a result of gene regulation?
|B)||One gene : many proteins|
|E)||All of the choices result from gene regulation.|
In bacteria, transcriptional regulation by ________ proteins is called ________ control.
Which of the following contributes to the combinatorial control of eukaryotic gene expression?
|E)||All of the choices contribute to combinatorial control in eukaryotes.|
True or False: A core promoter is able to produce low level basal transcription by itself.
Which of the following is not an example of genetic regulation?
|A)||E. coli decreases expression of beta-galactosidase in response to lactose in the growth medium.|
|B)||The cells in a developing fetus synthesize the same proteins in each stage of development.|
|C)||Brain cells produce a different set of proteins than muscle cells.|
|D)||A cell has encountered DNA damage and expresses a set of repair RNA molecules to fix the damage.|
|E)||E. coli produces a polycistronic mRNA molecule from the lac operon in response to the presence of glucose in its surrounding environment.|
At which of the following steps do eukaryotes perform genetic regulation?
III: mRNA processing
VI: Protein synthesis
|A)||i, ii, iii|
|C)||ii, iii, iv|
|D)||i, ii, iii, iv|
At which of the following steps do bacteria most frequently perform genetic regulation?
|E)||Bacteria perform genetic regulation equally at all of the steps listed.|
True or False: A single molecule of mRNA that has coding sequences for more than one structural protein is called polycistronic.
Which of the following statements about lactose regulation in E. coli is incorrect?
|A)||The protein product of the lacY gene allows lactose to be taken up by the cell.|
|B)||The binding of the lac repressor protein to the operator region is dependent on the presence of allolactose.|
|C)||The lac operon is inducible.|
|D)||The lacZ, lacY, lacA and lacI genes comprise the lac operon.|
|E)||The protein product of the lacZ gene coverts lactose to glucose and galactose.|
The lac operator region is an example of a ________ and the product of the lacI gene is an example of a ________.
|A)||cis-acting element; cis-acting element|
|B)||trans-acting element; trans-acting element|
|C)||cis-acting element; trans-acting element|
|D)||trans-acting element; cis-acting element|
|E)||positive control ; negative control|
Under which of the following conditions would lac operon expression in E. coli be minimal?
|A)||High levels of glucose, low levels of lactose|
|B)||Low levels of glucose, high levels of lactose|
|C)||High levels of glucose, high levels of lactose|
|D)||Low levels of glucose, low levels of lactose|
|E)||lac operon expression is never minimized|
True or False: Tryptophan acts as an inducer of the trp operon by binding to the trp repressor protein, releasing it from the trp operator.
Repressible operons are typically involved in ________ and inducible operons are typically involved in ________.
Which of the following would most likely be found in prokaryotes?
|A)||Generalized transcription factors|
|C)||Arrangement of structural genes in an operon|
|E)||All of the choices would equally likely be found in eukaryotes.|
Chromatin takes part in gene regulation through
|C)||the location of nucleosomes.|
|D)||closed conformation and open conformation.|
|E)||closed conformation, open conformation, and the location of nucleosomes.|
Which of the following statements about the regulation of gene expression in eukaryotes is incorrect?
|A)||Chromatin in the closed conformation is more easily transcribed than chromatin in the open conformation.|
|B)||Acetylated histones do not bind as tightly to DNA as non-acetylated histones.|
|C)||ATP-dependent chromatin remodeling enzymes can be recruited to a site of transcription by activator proteins.|
|D)||Steroid hormone receptor molecules often function as transcriptional activators.|
|E)||All of these choices about the regulation of gene expression in eukaryotes are correct.|
True or False: Alternative splicing is a form of gene regulation that utilizes the same molecule of mRNA to produce different proteins?
True or False: DNA methylation typically enhances the expression of a eukaryotic gene.
Which one of the following statements about alternative splicing is correct?
|A)||Alternative splicing leads to different protein products with very different functions.|
|B)||Alternative splicing enables an organism to increase the size of its genome without having to increase the size of its proteome.|
|C)||Alternative splicing is common in all eukaryotes, but uncommon in prokaryotes.|
|D)||Alternate forms of a protein are made by different cell types, or at different stages of development, from a single gene in the genome.|
|E)||All of the choices about alternative splicing are correct.|
Which of the following statements about RNA interference is incorrect?
|A)||RNA interference is an example of genetic regulation at the level of transcription.|
|B)||Precursor miRNAs form a hairpin loop and are then hydrolyzed by dicer.|
|C)||MiRNAs associate with cellular proteins and then bind to target sequences in mRNA.|
|D)||In animals, RISC inhibits translation.|
|E)||In plants, RISC targets a mRNA for degradation.|