Biology, Eighth Edition (Raven)
DNA: The Genetic Material
Learning OutcomesChapter 14
- Describe the experiments that first supported the hypothesis that a cell’s hereditary material is located in the nucleus.
- Understand the theory and conclusions associated with the Griffith and Avery experiments using Pneumococcus and mice.
- Explain the evidence that supports the identity of DNA as hereditary material.
- Identify the three subunits of DNA and describe how they are put together to construct an intact molecule.
- Understand the importance of Chargaff’s rules and the complementary nature of nucleotide bases.
- Describe Watson and Crick’s three--dimensional model of DNA based upon Franklin’s X-ray crystallography.
- Know what is meant by semiconservative replication of DNA and how it was determined.
- Explain the process of semidiscontinuous replication in both strands of the DNA double helix.
- Understand the one gene-one polypeptide hypothesis and the experimental evidence behind it.