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Microbiology, Fifth Edition
Microbiology, 5/e
Lansing M Prescott, Augustana College
Donald A Klein, Colorado State University
John P Harley, Eastern Kentucky University
Specific Immunity

Chapter Objectives

After reading this chapter you should be able to:
  • compare and contrast specific immunity and nonspecific immunity
  • discuss antigens, haptens, superantigens, and CD antigens
  • compare and contrast IgG, IgM, IgA, IgD, and IgE antibodies
  • discuss the mechanisms by which antibody diversity is generated
  • describe the clonal selection theory
  • discuss the role of T-cell receptors and MHC molecules in the functioning of T cells
  • describe the roles of cytotoxic T cells, T-helper cells, and T-suppressor cells in specific immunity
  • describe B-cell activation
  • describe the outcomes in vivo of antigen-antibody binding
  • describe the activation of complement by the classical pathway
  • describe the mechanisms used to establish immune tolerance
  • list the ways antibodies, lymphocytes, and nonspecific defenses provide immunity to viral and bacterial pathogens








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