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1 |  |  The lymphatic system consists of _______. |
|  | A) | lymphatic vessels and lymphoid organs |
|  | B) | all of the plasma component of the bloodstream |
|  | C) | all fluids inside the body's cells |
|  | D) | all liquids in the body whether inside cells or in spaces between tissues |
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2 |  |  The lymphatic system _______. |
|  | A) | takes up excess tissue fluid and returns it to the bloodstream |
|  | B) | absorbs fats in the intestinal villi and transports them to the bloodstream |
|  | C) | defends the body against disease |
|  | D) | All of the above are correct. |
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3 |  |  The movement of lymph within lymphatic vessels is dependent upon _______. |
|  | A) | residual blood pressure forcing the plasma through the blood vessels |
|  | B) | suction from the contracting lymph nodes |
|  | C) | skeletal muscle contraction and the action of one-way valves |
|  | D) | active transport of lymph by cilia lining the lymphatic system |
|  | E) | ameboid movement of the cellular component of the lymph, primarily the T-cells that "travel" |
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4 |  |  Lymph is prevented from flowing backwards by _______. |
|  | A) | blood pressure |
|  | B) | suction from the contracting lymph nodes |
|  | C) | one-way valves |
|  | D) | cilia lining the lymphatic system |
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5 |  |  The lymphatic system is _________. |
|  | A) | a two-way transport system with fluids and cells moving both directions |
|  | B) | a continuous closed circulation running parallel to the arteries and veins |
|  | C) | a one-way system collecting the lymph from body tissues and spaces and reintroducing it to the bloodstream |
|  | D) | a one-way system collecting lymph from body spaces and soaking it into the body cells |
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6 |  |  Tissue fluid in the lymphatic system is called ________. |
|  | A) | plasma |
|  | B) | hemoplasma |
|  | C) | Ringer's solution |
|  | D) | lymph |
|  | E) | universal solvent |
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7 |  |  The thoracic duct serves |
|  | A) | the lower extremities. |
|  | B) | the abdomen. |
|  | C) | the left arm. |
|  | D) | all of the above. |
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8 |  |  The thoracic and right lymphatic ducts return lymph to the ________. |
|  | A) | dorsal aorta |
|  | B) | abdominal cavity |
|  | C) | heart ventricles |
|  | D) | peritoneal cavities |
|  | E) | subclavian veins |
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9 |  |  The subclavian veins are cardiovascular veins in the abdomen. |
|  | A) | True |
|  | B) | False |
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10 |  |  ________ is localized swelling caused by accumulation of tissue fluid. |
|  | A) | Immune deficiency disease |
|  | B) | Allergies |
|  | C) | Autoimmune disease |
|  | D) | Edema |
|  | E) | Hemolytic disease |
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11 |  |  Lymph flows from lymphatic capillaries into ever-larger lymphatic vessels and finally to a lymphatic duct. |
|  | A) | True |
|  | B) | False |
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12 |  |  Each nodule of a lymph node contains a sinus filled with _______. |
|  | A) | lymphocytes and macrophages |
|  | B) | red marrow |
|  | C) | red blood cells |
|  | D) | lymph causing edema |
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13 |  |  Which of the following is NOT a lymphoid organ: |
|  | A) | red bone marrow |
|  | B) | adenoids |
|  | C) | spleen |
|  | D) | tonsils |
|  | E) | kidney |
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14 |  |  Only red blood cells originate in the red bone marrow. |
|  | A) | True |
|  | B) | False |
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15 |  |  All bones in an adult have red bone marrow. |
|  | A) | True |
|  | B) | False |
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16 |  |  The red bone marrow consists of a network of connective tissue fibers called reticular fibers. |
|  | A) | True |
|  | B) | False |
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17 |  |  The tonsils and adenoids (pharyngeal tonsils) are composed of partly encapsulated lymph nodules. |
|  | A) | True |
|  | B) | False |
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18 |  |  The spleen is located in the lower right thoracic cavity just above the diaphragm. |
|  | A) | True |
|  | B) | False |
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19 |  |  The spleen's sinuses are filled with _______. |
|  | A) | lymph |
|  | B) | blood |
|  | C) | water |
|  | D) | salts |
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20 |  |  A spleen nodule contains ________. |
|  | A) | the factory that produces platelets |
|  | B) | red pulp and white pulp |
|  | C) | a reservoir of glucose stored as glycogen |
|  | D) | hormone-producing islets |
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21 |  |  Red pulp contains only red blood cells. |
|  | A) | True |
|  | B) | False |
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22 |  |  Lymph is cleansed in lymph nodes and blood is cleansed in the spleen. |
|  | A) | True |
|  | B) | False |
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23 |  |  White pulp contains mostly _______. |
|  | A) | lymphocytes |
|  | B) | red blood cells |
|  | C) | macrophages |
|  | D) | osteoblasts |
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24 |  |  The thymus is located _______. |
|  | A) | in the neck |
|  | B) | in the upper left abdominal cavity just beneath the diaphragm |
|  | C) | along the trachea behind the sternum |
|  | D) | along the intestinal wall |
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25 |  |  The thymus is smaller in children than in adults. |
|  | A) | true |
|  | B) | false |
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26 |  |  The thymus secretes ________. |
|  | A) | antibodies |
|  | B) | hormones that mature the red blood cells |
|  | C) | macrophages |
|  | D) | lymph and is the main "lymph factory" |
|  | E) | thymosin, a hormone thought to aid in maturation of T lymphocytes |
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27 |  |  T lymphocytes mature in the ________. |
|  | A) | spleen |
|  | B) | red bone marrow |
|  | C) | thymus |
|  | D) | lymph nodes throughout the body |
|  | E) | thyroid |
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28 |  |  Immunity is the ability of the body to defend itself against ________. |
|  | A) | infectious agents including bacteria and viruses |
|  | B) | foreign cells |
|  | C) | cancer cells |
|  | D) | all of the above |
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29 |  |  The nonspecific defenses are ___________. |
|  | A) | barriers to entry, the inflammatory reaction, natural killer cells, and protective proteins |
|  | B) | antibodies, antigens, and antimatter |
|  | C) | the spleen and thymus |
|  | D) | allergies, edema and regurgitation |
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30 |  |  Barriers to entry of microbes include __________. |
|  | A) | oil skin secretions and stomach acids |
|  | B) | normal harmless bacteria that prevent pathogens from taking up residence |
|  | C) | mucous membranes that line the respiratory, digestive and urinary tracts |
|  | D) | skin that lines the outer surface of the body |
|  | E) | all of the above help bar entry by microbes |
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31 |  |  The stomach has a basic pH inhibiting growth of bacteria. |
|  | A) | True |
|  | B) | False |
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32 |  |  The ________ reaction is a series of events occurring whenever the skin is broken due to a minor injury. |
|  | A) | allergic |
|  | B) | antibody |
|  | C) | complement fixation |
|  | D) | inflammatory |
|  | E) | suppressor T-cell |
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33 |  |  ________ are molecules initiating nerve impulses resulting in pain. |
|  | A) | Analgesics |
|  | B) | Immunoglobulins |
|  | C) | Kinins |
|  | D) | Histamines |
|  | E) | Suppressins |
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34 |  |  Histamine and kinins cause capillaries to constrict and become less permeable. |
|  | A) | True |
|  | B) | False |
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35 |  |  Any break in the skin can allow microbes to enter the body. |
|  | A) | True |
|  | B) | False |
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36 |  |  How can neutrophils and monocytes reach an infection site from the bloodstream? |
|  | A) | the blood vessels rupture at a site of infection |
|  | B) | neutrophils and monocytes are amoeboid and can pass through capillary walls |
|  | C) | they are small and diffuse across membranes just like food and gas molecules. |
|  | D) | they move upstream in the lymph system |
|  | E) | the portable T lymphocyte differentiates into neutrophils and monocytes when it arrives at the site of infection |
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37 |  |  What can happen to a bacterium that crosses the skin barrier and enters tissues? |
|  | A) | histamine will poison bacteria |
|  | B) | neutrophils phagocytize the bacteria |
|  | C) | bacteria liberate a growth factor that in turn increases the numbers of white blood cells that attack bacteria |
|  | D) | all human tissues reject the bacterium and destroy it with lysosomes |
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38 |  |  When monocytes leave the bloodstream, they differentiate into ________. |
|  | A) | complement proteins |
|  | B) | antibodies |
|  | C) | interferon |
|  | D) | macrophages |
|  | E) | suppressor T-cells |
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39 |  |  Some tissues have ______ that routinely act as scavengers, devouring old blood cells and other debris. |
|  | A) | resident macrophages |
|  | B) | suppressor T-cells |
|  | C) | backup neutrophils |
|  | D) | complimentary B-cells |
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40 |  |  Pus indicates that ______________. |
|  | A) | body tissues are dying |
|  | B) | the body is trying to overcome infection |
|  | C) | too much lymph has built up |
|  | D) | the inflammatory response has failed to defend against bacterial invasion |
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41 |  |  Complement is activated when ________ . |
|  | A) | the inflammatory response has failed to defend against bacterial invasion |
|  | B) | antibodies have failed to defend against bacterial invasion |
|  | C) | microbes enter the body |
|  | D) | interferon is produced by viruses |
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42 |  |  Complement proteins bind to the surface of microbes already coated with antibodies, and release chemicals that attract phagocytes to the scene. |
|  | A) | True |
|  | B) | False |
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43 |  |  A virus-infected cell produces and secretes _______. |
|  | A) | allergin |
|  | B) | antigen |
|  | C) | antibody |
|  | D) | complement |
|  | E) | interferon |
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44 |  |  A/an ________ is usually a protein or polysaccharide chain of a glycoprotein molecule that the body recognizes as "non-self." |
|  | A) | allergin |
|  | B) | antigen |
|  | C) | antibody |
|  | D) | complement |
|  | E) | interferon |
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45 |  |  The immune system is chemically able to tell "self" from "non-self" based on a lock-and-key receptor-antigen fit. |
|  | A) | True |
|  | B) | False |
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46 |  |  B lymphocytes mature in the bloodstream. |
|  | A) | True |
|  | B) | False |
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47 |  |  T lymphocytes mature in the ________ . |
|  | A) | bone marrow |
|  | B) | lymph in the general lymphatic system |
|  | C) | thymus gland |
|  | D) | thyroid gland |
|  | E) | spleen |
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48 |  |  B cells give rise to plasma cells which produce ________. |
|  | A) | allergin |
|  | B) | antigen |
|  | C) | antibody |
|  | D) | complement |
|  | E) | interferon |
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49 |  |  Antibodies bind with antigens in a lock-and-key manner. |
|  | A) | True |
|  | B) | False |
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50 |  |  T cells produce antibodies. |
|  | A) | True |
|  | B) | False |
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51 |  |  Certain T cells attack and destroy antigen-bearing cells. |
|  | A) | True |
|  | B) | False |
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52 |  |  There is a different lymphocyte type for each possible antigen. |
|  | A) | True |
|  | B) | False |
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53 |  |  A plasma cell is a mature B cell that mass produces ________. |
|  | A) | allergens |
|  | B) | antigens |
|  | C) | antibodies |
|  | D) | complement |
|  | E) | interferon |
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54 |  |  A B cell does not clone until its antigen is present. |
|  | A) | True |
|  | B) | False |
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55 |  |  When B cells undergo clonal expansion, they produce plasma cells and memory B cells. |
|  | A) | True |
|  | B) | False |
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56 |  |  Defense by T cells is called antibody-mediated immunity. |
|  | A) | True |
|  | B) | False |
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57 |  |  Humoral immunity is so called because antibodies are present in the ________. |
|  | A) | tissues |
|  | B) | red blood cells |
|  | C) | blood and lymph |
|  | D) | upper arm bone or "humerus" |
|  | E) | cranium |
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58 |  |  The most common type of antibody is a protein molecule with two arms. |
|  | A) | True |
|  | B) | False |
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59 |  |  The main antibody type in circulation is _______. |
|  | A) | IgG |
|  | B) | IgM |
|  | C) | IgD |
|  | D) | IgA |
|  | E) | IgE |
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60 |  |  ________ is the largest antibody. |
|  | A) | IgG |
|  | B) | IgM |
|  | C) | IgD |
|  | D) | IgA |
|  | E) | IgE |
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61 |  |  IgA antibodies are found in _______. |
|  | A) | body secretions such as saliva and milk |
|  | B) | blood and on mast cells in tissues |
|  | C) | lymph |
|  | D) | general plasma |
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62 |  |  IgG antibodies _________. |
|  | A) | are responsible for allergic reactions |
|  | B) | stimulate complement production |
|  | C) | bind to pathogens their toxins |
|  | D) | trigger inflammation |
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63 |  |  IgM antibodies _________. |
|  | A) | attack microbes |
|  | B) | activate complement and clump cells |
|  | C) | attack bacterial toxins |
|  | D) | are responsible for allergic reactions |
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64 |  |  IgA antibodies attack microbes and bacterial toxins. |
|  | A) | True |
|  | B) | False |
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65 |  |  ________ antibodies are responsible for allergic reactions. |
|  | A) | IgG |
|  | B) | IgM |
|  | C) | IgD |
|  | D) | IgA |
|  | E) | IgE |
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66 |  |  There is/are ________ main types of T cell(s). |
|  | A) | one |
|  | B) | two |
|  | C) | three |
|  | D) | four |
|  | E) | five |
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67 |  |  Which of the following is NOT a type of T cell? |
|  | A) | cytotoxic T cells |
|  | B) | helper T cells |
|  | C) | memory T cells |
|  | D) | plasma T cell |
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68 |  |  Cytotoxic T cells attack and destroy ________. |
|  | A) | bacteria |
|  | B) | viruses |
|  | C) | cells that produce toxins or poisons |
|  | D) | antigen-bearing cells |
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69 |  |  Cytotoxic T cells storage vacuoles contain _______. |
|  | A) | antibodies |
|  | B) | perforin molecules |
|  | C) | complement |
|  | D) | IgG |
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70 |  |  Perforin molecules function to ________. |
|  | A) | perforate a cell membrane |
|  | B) | stimulate production of complement |
|  | C) | trigger production of interferon |
|  | D) | label a cell for attack by cytotoxic T cells |
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71 |  |  Perforin molecules form holes in plasma membranes, allowing _________. |
|  | A) | water and salt to enter a cell |
|  | B) | vital cell contents to leak out |
|  | C) | macrophages to phagocytize cells |
|  | D) | IgG to bind with foreign proteins |
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72 |  |  ________ T cells are the only T cells involved in cell-mediated immunity. |
|  | A) | Cytotoxic |
|  | B) | Helper |
|  | C) | Memory |
|  | D) | Suppressor |
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73 |  |  HIV that causes AIDS infects _______. |
|  | A) | helper T cells |
|  | B) | cytotoxic T cells |
|  | C) | suppressor T cells |
|  | D) | memory T cells |
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74 |  |  Helper T cells regulate immunity by increasing the response of other immune cells. |
|  | A) | True |
|  | B) | False |
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75 |  |  When exposed to an antigen, helper T cells enlarge and secrete messenger molecules called ________. |
|  | A) | antibodies |
|  | B) | perforin |
|  | C) | complement |
|  | D) | IgG |
|  | E) | cytokines |
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76 |  |  Cytokines _________. |
|  | A) | stimulate white blood cell formation |
|  | B) | trigger inflammation |
|  | C) | depress antibody production |
|  | D) | make the body more susceptible to cancer |
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77 |  |  ________ are antibodies of one specific type, all produced by plasma cells derived from the same B cell, and capable of identifying unique cells and infectious agents. |
|  | A) | Lymphokines |
|  | B) | Inflammatory reactions |
|  | C) | Complement fixations |
|  | D) | Antibody-mediated immunity |
|  | E) | Monoclonal antibodies |
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78 |  |  With the human ABO blood types in the below transfusions, which person would safely receive blood lacking foreign antigens? |
|  | A) | a type A person received type B blood |
|  | B) | a type B person received type A blood |
|  | C) | a type O person received type B blood |
|  | D) | a type A person received type AB blood |
|  | E) | a type A person received type O blood |
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79 |  |  Why is hemolytic disease of the newborn (Rh-conflict) described as a likely problem only when the mother is Rh-negative and the father is Rh-positive? |
|  | A) | a type Rh-negative father is not possible since it is sex-linked |
|  | B) | the type Rh-negative is so rare that Rh-negative fathers are too uncommon |
|  | C) | a type Rh-negative fetus in an Rh-positive mother does not expose the mother to any new antigens and therefore does not trigger any immune response |
|  | D) | this was just the way the textbook gave the possible example and the reverse situation is just as much a problem |
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80 |  |  When an immune system overreacts to an antigen or forms antibodies to substances that are usually NOT recognized as foreign, it results in _______. |
|  | A) | immune deficiency disease |
|  | B) | allergic response |
|  | C) | autoimmune disease |
|  | D) | edema |
|  | E) | hemolytic disease |
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81 |  |  Myasthenia gravis, multiple sclerosis, lupus erythematosus, and rheumatoid arthritis are examples of ________. |
|  | A) | immune deficiency diseases |
|  | B) | normal inflammatory reactions |
|  | C) | autoimmune diseases |
|  | D) | failure of the B cells to defend the body |
|  | E) | failure of the T cells to defend the body |
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82 |  |  Thanks to new biotechnology, there are now cures for all autoimmune diseases. |
|  | A) | True |
|  | B) | False |
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