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Multiple Choice Quiz
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1

A true fungal pathogen must exhibit what characteristic?
A)Produce spores
B)Produce mycelia
C)Thermal dimorphism
D)Be transmitted by the respiratory route
E)Be distributed worldwide
2

Which statement regarding the opportunistic fungal pathogens is incorrect?
A)They have a limited degree of virulence.
B)They always display thermal dimorphism.
C)They are spread by the respiratory or mucocutaneous route.
D)They stimulate only weak and short-lived immunity.
E)They are distributed worldwide.
3

Where is Histoplasma capsulatum found within the United States?
A)Desert southwest
B)Alaska
C)Northwest
D)Ohio and Mississippi river valleys
E)Central plains
4

What are the most prevalent of all fungal infections?
A)Dermatophytoses
B)Histoplasmosis
C)Candidiasis
D)Cryptococcosis
E)Coccidioidomycosis
5

Dermatophytoses can be spread by all but which of the following?
A)Gymnasiums
B)Public facilities
C)Personal articles
D)Swimming pools
E)Sexual contact
6

What component of the fungi is most involved in initiating mycoses?
A)Mycelia
B)Hyphae
C)Spores
D)Rhizoids
E)Yeasts
7

Why are yeasts more invasive than hyphal forms of fungi?
A)Because they multiply more rapidly.
B)Because they cannot tolerate high temperatures.
C)Because the hyphal forms localize in tissues.
D)Because they produce toxins.
E)Because they invoke an inflammatory response.
8

Which fungus causes mycoses of the hair, skin, and nails?
A)Cryptococcus
B)Aspergillis
C)Sporothrix
D)Blastomyces
E)All dermatophytes
9

Which class of antifungal drugs inhibits an enzyme in egosterol synthesis and is administered topically to treat dermatophyte infections?
A)Polyenes
B)Axoles
C)Those that inhibit nucleic acid synthesis
D)Allylamines
E)Those that inhibit cell division
10

What type of fungal infection involves the stratum corneum and occasionally the upper dermis?
A)Systemic
B)Cutaneous
C)Acute
D)Superficial
E)Subcutaneous
11

Who experiences the majority of cases of histoplasmosis?
A)Elderly females
B)Adult males
C)Infants
D)Teenage females
E)Adolescent males
12

Where is the primary location of Histoplasma capsulatum microconidia growth?
A)Within the cytoplasm of macrophages
B)Within red blood cells
C)In the circulatory system
D)In the cerebrospinal fluid
E)In the meninges
13

Which fungus is the most virulent of all mycotic pathogens?
A)Histoplasma capsulatum
B)Blastomyces dermatitidis
C)Coccidioides immitis
D)Paracoccidioides brasiliensis
E)Candida albicans
14

Outbreaks of coccidioidomycosis have been associated with all but which of the following?
A)Farming
B)The Northridge, California earthquake
C)Mining
D)Hurricane Isabel
E)Archeological digs
15

How is coccidioidomycosis diagnosed?
A)Examination of fecal material for hyphae
B)Examination of cerebrospinal fluid for Gram-negative cocci
C)Examination of the throat for the presence of a pseudomembrane
D)Examination of the chest for local abscesses
E)Examination of sputum, spinal fluid, or biopsies for spherules
16

Which is not a chief target of blastomycosis infection?
A)Dogs
B)Cats
C)Birds
D)Horses
E)Humans
17

Most incidents of human sporotrichosis arise following what event?
A)Inhalation of spores
B)A puncture or scratch wound
C)Consumption of contaminated food
D)The bite of a tick
E)Consumption of contaminated water
18

What is the causative agent of athlete's foot?
A)Candida albicans
B)Epidermophyton
C)Coccidioides
D)Microsporum
E)Trichophyton
19

What is the Latin name that corresponds to athlete's foot?
A)Tinea corporis
B)Tinea pedia
C)Tinea barbae
D)Tinea cruris
E)Tinea unguium
20

What organisms cause fungal infections that are strictly confined to nonliving tissues and its derivatives?
A)Sporothrix
B)Blastomyces
C)Coccidioides
D)Dermatophytes
E)Cryptococcus
21

Candida albicans causes local infections in all but which of the following sites?
A)Endocardium
B)Mouth
C)Pharynx
D)Vagina
E)Lungs
22

What factor is important in the pathogenesis of Cryptococcus neoformans?
A)Pili
B)Hyphae
C)Capsule
D)Glycoprotein spikes
E)Lipopolysaccharide
23

What is the reservoir for Cryptococcus neoformans?
A)Humans
B)Soil
C)Rodents
D)Birds
E)Pigs
24

Who typically develops Pneumocystis carinii infections?
A)People with deficient immune systems
B)Middle aged men
C)Infants
D)Rose gardeners
E)IV drug users
25

Where do Aspergillus infections usually occur?
A)Skin
B)Mouth
C)Gastrointestinal tract
D)Kidneys
E)Lungs





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