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Multiple Choice Quiz
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1

From where do most DNA viruses assemble and bud?
A)Cytoplasm
B)Golgi apparatus
C)Nucleus
D)Mitochondria
E)Endoplasmic reticulum
2

From where do most RNA viruses assemble and release?
A)Cytoplasm
B)Golgi apparatus
C)Nucleus
D)Mitochondria
E)Endoplasmic reticulum
3

What term describes a virus that crosses the placenta from an infected mother to the embryo or fetus?
A)Zoonotic
B)Teratogenic
C)Oncogenic
D)Cytopathic
E)Virulent
4

Which statement regarding the poxviruses is incorrect?
A)They are the largest and most complex of all the animal viruses.
B)They have the largest genome of all viruses.
C)They multiply in the cytoplasm.
D)They are non-enveloped DNA viruses.
E)Their sites of multiplication within infected cells appear as inclusion bodies.
5

Which is the causative agent of smallpox?
A)Ebola virus
B)Herpes virus
C)Vaccinia virus
D)Monkeypox virus
E)Variola virus
6

When did the last naturally occurring case of smallpox occur?
A)2003
B)1995
C)1977
D)1950
E)1918
7

What type of vaccine is the current smallpox vaccine?
A)Acellular
B)Toxoid
C)Attenuated
D)Live
E)Recombinant
8

Smallpox can be spread by both exposure to skin scabs and by what other method?
A)Bites from infected insects
B)Fecal-oral route
C)Respiratory route
D)Sexual transmission
E)Bites from infected animals
9

What poxvirus caused the June 2003 outbreak of disease in the Midwestern United States?
A)Cowpox
B)Prairie dog pox
C)Ratpox
D)Monkeypox
E)Mousepox
10

Which statement regarding the herpesvirus family is incorrect?
A)They replicated in the host cell cytoplasm
B)They tend to be latent viruses and cause recurrent infections
C)They are enveloped viruses
D)They often incorporate their nucleic acid into the host genome
E)They commonly cause infections in immunocompromised individuals
11

What herpesvirus is the causative agent of genital infections?
A)Cytomegalovirus
B)Herpes simplex-2
C)Epstein-Barr virus
D)Herpes simplex-1
E)Varicella zoster
12

Which of the following stimuli does not trigger a recurrence of a herpes simplex virus infection?
A)Exposure to cold air
B)Fever
C)Mechanical injury
D)Exposure to UV radiation
E)Stress
13

What are the targets for herpes simplex viruses?
A)Neurons
B)Epidermis
C)Hepatocytes
D)Meninges
E)Mucous membranes
14

Healthcare workers may develop what type of herpes lesion if they touch patients or patients' secretions without hand protection?
A)Cold sores
B)Herpetic keratitis
C)Genital herpes
D)A "cigarette burn" pattern of infection
E)A herpetic whitlow
15

What organism causes the most common sporadic form of viral encephalitis in the United States?
A)Rabies virus
B)Herpes simplex virus
C)Smallpox
D)Neisseria meningitidis
E)Varicella-zoster
16

What antiviral agent is highly specific for herpes simplex viruses?
A)Valacyclovir
B)Interferon
C)Acyclovir
D)Ganicyclovir
E)Foscarnet
17

What is the portal of entry for varicella-zoster virus?
A)Respiratory epithelium
B)Mouth
C)Conjunctiva
D)Through a break in the skin
E)The genitourinary tract
18

When are people infected with varicella-zoster virus most contagious?
A)1-2 days prior to the development of the rash
B)When the rash appears
C)When the skin lesions become itchy
D)When the lesions become encrusted
E)When the scabs fall off
19

What group tends to develop a more virulent form of cytomegalovirus infection?
A)Women of childbearing age
B)Young adults
C)IV drug abusers
D)Male homosexuals
E)Newborns
20

Both Burkitt lymphoma and infectious mononucleosis are caused by what virus?
A)Cytomegalovirus
B)Epstein-Barr virus
C)Varicella-zoster virus
D)Herpes simplex-1
E)Adenovirus
21

Where is the niche for Epstein-Barr virus in humans?
A)Respiratory epithelium
B)Thoracic nerves
C)Liver
D)Lymphoid tissue and salivary glands
E)Conjunctiva
22

Patients experiencing chronic fatigue syndrome display all but which of the following symptoms?
A)Disabling fatigue
B)Abnormal levels of CD4 T cells
C)Low levels of NK cells
D)Underactive inflammatory response
E)Enlarged lymph nodes
23

What is the only DNA virus that causes hepatitis?
A)Hepatitis A virus
B)Hepatitis B virus
C)Hepatitis C virus
D)Hepatitis D virus
E)Hepatitis E virus
24

What group is not at risk for contracting hepatitis B virus?
A)Healthcare workers
B)Drug addicts
C)Teachers
D)Homosexual males
E)Sexually promiscuous individuals
25

What is the most common sexually transmitted disease in the United States?
A)Gonorrhea
B)Syphilis
C)Human papillomavirus
D)Chlamydia
E)AIDS





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