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1 | | Which of the following is a correct definition of genetics? |
| | A) | The study of transmission of traits from parent to offspring. |
| | B) | The study of genes and traits defined by genes. |
| | C) | The study of DNA. |
| | D) | The study of variation between members of a species. |
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2 | | Which statement about nucleic acids is not correct? |
| | A) | They are macromolecules. |
| | B) | They are organic molecules. |
| | C) | They are typically long, linear molecules. |
| | D) | None; all of these statements are correct. |
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3 | | What is the main function of DNA? |
| | A) | It stores information for protein synthesis. |
| | B) | It can be mutated. |
| | C) | It directs the process of protein synthesis. |
| | D) | It provides energy for the cell. |
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4 | | Identify the correct order of organization of genetic material, from largest to smallest. |
| | A) | Genome, chromosome, gene, nucleotide |
| | B) | Gene, chromosome, nucleotide, genome |
| | C) | Chromosome, gene, genome, nucleotide |
| | D) | Chromosome, genome, nucleotide, gene |
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5 | | Which statement is correct about Rieger syndrome in humans? (See Fig 1.1) |
| | A) | The gene which, when mutant, causes this syndrome is located on the X chromosome. |
| | B) | This gene is required for production of an essential blood clotting factor, Factor XI. |
| | C) | It is located on the same chromosome as genes which, when mutant, cause Huntington disease and Hepatocellular carcinoma. |
| | D) | Rieger syndrome has not been demonstrated to have a genetic cause. |
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6 | | Which of these might be a valid scientific reason for creating mice that glow green? |
| | A) | We thought they might make popular pets. |
| | B) | It served as an effective demonstration that an extra gene could be incorporated into and expressed in most tissues of a model organism. |
| | C) | Glowing mice might be effective "flashlights" in search and rescue applications. |
| | D) | Glowing mice could be easily distinguished from unmanipulated animals. |
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7 | | A gene: |
| | A) | Can be described as a unit of heredity. |
| | B) | Contains information to produce a particular protein. |
| | C) | Affects traits at the cellular level. |
| | D) | Can exist in many forms. |
| | E) | All of the above. |
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8 | | Haploid cells in the human body: |
| | A) | Are a typical example of human cells. |
| | B) | Are caused by allelic variation. |
| | C) | Are gametes, which allow sexual reproduction. |
| | D) | Contain 46 chromosomes. |
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9 | | Which field of genetics is the oldest? |
| | A) | Transmission genetics. |
| | B) | Molecular genetics. |
| | C) | Population genetics. |
| | D) | Developmental genetics. |
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10 | | Which technique is most likely to be used by a molecular geneticist? |
| | A) | Production of a new mutant allele of an interesting gene. |
| | B) | Establishing crosses between genetic variants. |
| | C) | Analysis of the amount of genetic variation in a population of individuals. |
| | D) | Identification of a previously unknown species. |
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11 | | Morphs are an example of which level of genetic variation? |
| | A) | Molecular |
| | B) | Cellular |
| | C) | Organismal |
| | D) | Population |
| | E) | All of the above |
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12 | | Which is an example of a study that might be done by a transmission geneticist? |
| | A) | A comparison between many individuals indicates that the "short" variant of a particular gene seems to increase risk for alcoholism. |
| | B) | DNA sequencing allows geneticists to determine the difference between the short and long variants of a newly discovered gene. |
| | C) | Geneticists are able to clone and express a gene to produce human insulin. |
| | D) | A geneticist collects family histories in order to study the mechanism of transmission of a genetic disorder. |
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13 | | The human genome is distributed over 24 chromosomes. |
| | A) | True |
| | B) | False |
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14 | | Development of genetic technologies are often rejected at first even though they may be used to create great advances in medicine, agriculture, and many other fields. |
| | A) | True |
| | B) | False |
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15 | | Gene expression can be defined as the process of transcription and translation. |
| | A) | True |
| | B) | False |
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16 | | DNA is the most important macromolecule for correct cellular function. |
| | A) | True |
| | B) | False |
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17 | | The major difference between different cells in the same organism is that they have different DNA. |
| | A) | True |
| | B) | False |
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18 | | All sexually reproducing organisms are diploid. |
| | A) | True |
| | B) | False |
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19 | | Genetic composition of a species is stable over time. |
| | A) | True |
| | B) | False |
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20 | | Most traits are controlled by genetic variation. |
| | A) | True |
| | B) | False |
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