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1

Microbes are beneficial in all of the following activities EXCEPT:
A)producing infections.
B)to digest indigestible foods.
C)as decomposers.
D)for making cheese and sauerkraut.
2

There are thousands of microflora that live in our bodies. How do they benefit us?
A)assist disease-causing microbes
B)cause infectious organisms to grow and reproduce
C)help us digest otherwise indigestible materials
D)rid our bodies of vitamins and minerals
3

Diseases can be caused by __________.
A)bacteria
B)fungi
C)protozoans
D)viruses
E)All of the above are correct.
4

Microbes that cause disease are called:
A)saprophytes.
B)pathogens.
C)parasites.
D)none of the above.
5

Which of the following is NOT a virulence factor?
A)flagella
B)adhesion factors.
C)invasive factors.
D)survival mechanisms.
E)All of the choices are virulence factors.
6

Which virulence factor is correctly matched with its description?
A)Toxin -- breaks down connective tissue to spread.
B)Adhesion factors - a chemical when released is poisonous.
C)Capsule - for protection from phagocytosis.
D)Invasive factors - chemicals that allow bacteria to stick to cells
7

The study of the occurrence, distribution, and control of a disease in a population is called:
A)infectology.
B)pathogenicity.
C)pandemology.
D)epidemiology.
8

Which of the following is NOT a mode of pathogen transmission?
A)air-borne
B)vector-borne
C)direct contact
D)cold weather.
9

Which mode of pathogen transmission is correctly matched to its description?
A)vector-borne - an animal
B)air-borne - inanimate substance
C)direct contact - fomites
D)vehicle - droplet nuclei
10

Which of the following disease categories would affect the most people?
A)an endemic disease
B)an epidemic outbreak
C)a pandemic disease
D)a sporadic occurrence
11

An infectious agent that is always present in a population describes a/an:
A)pandemic.
B)sporadic occurrence.
C)endemic disease.
D)epidemic.
12

A host cell is critical to viral replication because the host cell
A)allows for budding of the virus.
B)enzymes make copies of the viral DNA.
C)gives the virus a place to attach.
D)proteins are made by the virus.
13

Place the steps of viral replication in the correct order. 1 - replication 2 - release 3 - attachment 4 - biosynthesis 5 - penetration 6 - maturation
A)2, 4, 6, 1, 3, 5
B)3, 5, 1, 4, 6, 2
C)3, 6, 1, 4, 5, 2
D)5, 3, 4, 1, 2, 6
14

After a virus penetrates a host cell, what is the next step in viral infection of the cell?
A)binding of the virus to the plasma membrane
B)removal of the capsid
C)replication of viral genetic material
D)production of viral proteins
15

Which of the following is NOT a reason for getting the flu again after you have already had it?
A)lowered resistance due to a similar cold virus
B)antigenic drift
C)antigenic shift
D)antigen changes in the capsid spikes
16

New influenza vaccines are produced for the US based on the influenza virus seen in:
A)South America
B)Southeast Asia
C)Eastern Europe.
D)Central Africa.
17

Virus capsids have spikes projecting from their surfaces of two antigens, ____ and ____ that are virulence factors.
A)R and D
B)N and C
C)D and H
D)N and H
18

Herpes Simplex Virus Type - 1 (HSV-1) causes:
A)Chicken pox
B)Cold sores
C)Genital blisters.
D)shingles.
19

Genital herpes infections caused by HSV-2 are very serious because
A)infected women cannot become pregnant.
B)these infections are often fatal to newborns.
C)they cause reoccurring cold sores.
D)they are activated by sunlight.
20

Which of the following is NOT true about the herpes virus, varizella-zoster?
A)It can remain latent for long periods of time.
B)It causes chickenpox in children.
C)It causes cold sores in people of all ages.
D)It causes shingles in adults.
21

Measles outbreaks sometimes occur on college campuses and spread quickly because the
A)vaccination given in infancy did not take or was given too early.
B)virus is airborne and spreads quickly in crowded conditions such as dormitories.
C)virus lives for long periods of time outside of the body on furniture.
D)Both a and b are correct.
22

The most effective route of cold virus transmission is by:
A)hand to hand contact.
B)airborne droplets.
C)a vehicle such as water.
D)a vector such as flies.
23

Cold viruses reside in the nasopharynx region because
A)in the nose they can fend off other competing pathogens.
B)it is warm and moist.
C)that is the first place they encounter a host organism.
D)they prefer environments slightly cooler than body temperature.
24

Prions are proteins, yet they cause diseases. Which of the following diseases are caused by prions?
A)common cold
B)leprosy
C)mad cow disease
D)shingles
25

Which part of the bacterial cell is sensitive to the Gram stain?
A)cell membrane
B)cell wall
C)cytoplasm
D)nuclear DNA
26

Which genus of bacteria causes the greatest variety of human diseases?
A)Clostridium botulinum
B)E. coli
C)M. tuberculosis
D)Streptococcus
27

A strong immune response to strep throat can lead to:
A)Scarlet fever.
B)impetigo.
C)pneumonia.
D)Rheumatic fever.
28

Which of the following diseases is a leading cause of heart disease worldwide?
A)meningitis
B)rheumatic fever
C)scarlet fever
D)staph infection
29

Tuberculosis affects which organ of the body?
A)heart
B)kidneys
C)lungs
D)skin
30

TB causes lesions in the lungs called:
A)tubercles.
B)tinea.
C)endospores.
D)capsids.
31

Food poisoning is caused by which of the following organisms?
A)Clostridium
B)Salmonella
C)Staphylococcus
D)All of the above cause food poisoning.
32

One might know in advance that food is contaminated with Clostridium botulinum because __________.
A)people who eat the food will develop tetanus
B)the can will bulge
C)the can will smell due to the gas produced
D)there will be spores on the surface
33

Fungi, including yeasts and molds, are responsible for all of the following diseases except one. Which disease is not caused by a fungus?
A)athlete's foot
B)oral thrush
C)ring worm
D)typhus
34

Candida albicans is a normal part of most people's microflora. However, candidiasis is observed when this normal balance is disrupted by which of the following conditions?
A)antibiotic treatment
B)immunodeficiency diseases
C)immunosuppressive drugs
D)All of the above can disrupt the normal microflora.
35

Which parasitic organism causes common ringworm of the scalp in humans?
A)flatworms
B)fungi
C)protozoans
D)round worms
36

Which of the following organisms transmit malaria?
A)dead animals
B)flies
C)mosquitoes
D)All of the above can transmit malaria.
37

Which of the following is the correct sequence of the life cycle of the Plasmodium?
A)enters human by mosquito bite --> sexual reproduction of the protozoan in the human --> liver --> damage to red blood cells
B)sexual reproduction in the human liver --> transmitted to another human by the mosquito --> enters the red blood cells which are then destroyed
C)sexual reproduction in the mosquito --> moves to human salivary glands through sting --> rapid reproduction in the salivary glands --> destruction of the liver cells
D)sexual reproduction in the mosquito --> move to mosquito salivary glands --> enters human --> damages liver and red blood cells
38

If you were camping, which of the following methods would rid water you collected from a stream of both Giardia and Cryptosporidium?
A)boiling
B)clearing with chlorine tablets
C)filtering through sand
D)None of the above methods work, there is currently no way to cleanse the water of these organisms.
39

Giardia infections are rampant in day-care centers because the cysts are found in ________.
A)human feces
B)the bird feeder
C)the drinking fountain water
D)untreated baby food
40

African sleeping sickness is transmitted by the:
A)tse-tse fly.
B)mosquito.
C)tick.
D)surface waters.
41

Which of the following are parasitic helminthes in humans?
A)Ascaris lumbricoides
B)Schistosoma
C)all flat worms and round worms
D)Only a and b are correct.
42

Why does poor sanitation lead to widespread parasitic flat worm and round worm infections?
A)Adult worms swim in surface waters.
B)Coughing and other respiratory ailments spread the infection.
C)Intermediate host organisms only live in unclean water.
D)Round worm and flat worm eggs are carried in human feces.







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