Biology (Raven), 10th Edition

Chapter 18: Genomics

Post-Test

1
Artificial chromosomes are used as
A)selectors.
B)sequencers.
C)cDNA sources.
D)vectors.
E)contigs.
2
Alu elements are part of which type of DNA sequence?
A)LINEs
B)SINEs
C)LTRs
D)Dead Transposons
E)Segmental Duplications
3
Which of the following is NOT a challenge to the use of genomics for society?
A)Behavioral genomics and its use to diagnose emotional or mental problems early.
B)Individual privacy rights and the need for large amounts of aggregate data in order to spot genetic trends.
C)Use of aggregate data to identify tendency towards disease and the use of these data by insurance companies and employers to improve their actuarial tables.
D)Questions about the ownership of genetic data and how these data can be applied to biotechnology.
E)All of these are challenges for the use of genomics.
4
Which of the following is NOT true of a comparison between a genetic and a physical map?
A)It is impossible to align physical and genetic maps.
B)They give different types of data because their units are based on different methods of analysis.
C)The physical map has a higher degree of resolution than the genetic map.
D)Cloned genes can be used directly to determine its position in a physical map, but must be mapped using a cross in the genetic map.
E)Physical map distances are uniform, while genetic map distances may vary between mapped gene pairs.
5
True or False: The shotgun cloning technique requires more computer processing than a clone-by-clone sequencing method.
A)True
B)False
6
How might genomics be most likely applied to alleviate stresses caused by environmental change, such as global warming?
A)We could engineer humans to tolerate higher temperatures.
B)Ethical dilemmas about using genetic information will break down boundaries regarding application of science, making the public more amenable to scientific solutions.
C)Genomes from vastly different organisms can be fused to create resistant hybrids.
D)Genes which provide resistance to environmental stresses in different species could be identified and exploited in agriculturally important organisms.
E)Genetics and global warming are incompatible fields of science.
7
An open reading frame (ORF) is distinguished by the presence of
A)a stop codon.
B)a start codon.
C)a sequence of DNA long enough to encode a protein.
D)None of the above.
E)All of the above.
8
What is a BLAST search?
A)A mechanism for aligning consensus regions during whole genome sequencing.
B)A search for similar gene sequences from other species.
C)A method of screening a DNA library.
D)A method for identifying ORFs.
E)A search for haplotype areas of DNA.
9
Errors in shotgun sequencing are reduced by the assembly of a _____ sequence.
A)rectified
B)collated
C)consensus
D)tagged
E)uniform
10
_______ refers to the conserved arrangements of segments of DNA in related genomes.
A)Haplotype
B)Physical map
C)linkage disequilibrium
D)Tandem clusters
E)Synteny
11
The coding region of a gene between a "start" and a "stop" codon is referred to as the
A)SRS.
B)PCR.
C)ORF.
D)EST.
E)TCL.
12
The number of proteins produced by the human genome is greater than the number of genes because of
A)alternative splicing.
B)pseudogenes.
C)EST amplification.
D)LTRs.
E)transposable elements.
13
Which of these is NOT a protein-encoding DNA in eukaryotes?
A)Simple sequence repeats
B)Single copy genes
C)Segmental duplication
D)Multiple gene families
E)Tandem clusters
14
Single copy genes silenced by mutation are called
A)RFLPs.
B)retrogenes.
C)pseudogenes.
D)homeogenes.
E)heterochromatin.
15
The tendency of genes not to randomize is called
A)nondisjunction.
B)transcription equilibrium.
C)genetic stabilization.
D)linkage disequilibrium.
E)genome conservation.
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