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Cytotoxic (Type II Hypersensitivity)
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Why does the immune system attack harmless materials? Although disease symptoms increase the response of the immune system, cells in the system will target anything that is not identifiable as self. In other words, anything that is not part of the organism will be attacked. This can lead to problems such as organ rejection and severe, sometimes life-threatening reactions to normally harmless substances. Presumably the reaction to all non-self substances allows the immune system to eliminate infectious agents such as viruses before they multiply to numbers where disease symptoms manifest themselves.

View the animation below, then complete the quiz to test your knowledge of the concept.





1People with type AB blood have
A)both type A and type B antigens on their red blood cells
B)both anti-A and anti-B antibodies in their serum
C)A antigen on their red blood cells and anti-B antibodies in their serum
D)a and b
E)none of the above


2When type B blood is given to a person with type A blood
A)B antigen from the donor reacts with anti-B antibody in the recipient
B)B antigen from the recipient reacts with anti-B antibody in the donor
C)B antigen from the donor reacts with anti-A antibody in the recipient
D)A antigen from the donor reacts with anti-A antibody in the recipient
E)no reaction occurs


3A person with type AB blood may receive
A)type A blood
B)type B blood
C)type AB blood
D)type O blood
E)all of the above


4People with type O blood can be universal donors because their red blood cells do not contain either A antigen or B antigen on their surface.
A)True
B)False


5A person with type O blood may receive blood from a person with type B blood.
A)True
B)False





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