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1
The utilization of statistical analysis via computer technology in order to better understand the complex genomes of living organisms is known as
A)biotechnology.
B)bioinformatics.
C)systems biology.
D)analytical biology.
E)analytical genetics.
2
Which of the following regarding prokaryotic genomes is incorrect?
A)Prokaryotic genomes are often circular
B)Prokaryotic genomes are believed to have evolved into eukaryotic cells through the union of bacteria and archea
C)Genetic processes in prokaryotic cells offer insight to more complex genetic processes in eukaryotic cells
D)Prokaryotic genomes are useful in the research of repeating sequences and their role in gene function.
E)All of the choices are true regarding prokaryotic genomes.
3
Which of the following statements most accurately describes the critical role of the genome in each species existence?
A)Genome stores information for the production of specific characteristics
B)The genome is passed on from parent to offspring generation after generation.
C)The genome is susceptible to change or mutation, allowing for diversity.
D)None of the statements describe critical roles of the genome
E)All choices describe critical roles of the genome.
4
Which of the following genomes could be found in a prokaryote?
A)A single circular chromosome
B)Multiple copies of a single type of circular chromosome
C)Single copies of more than one type of circular chromosome
D)A linear chromosome and a circular chromosome
E)All of the genome types can be found in prokaryotes.
5
On average, how many bacterial genes are found in one million base pairs of DNA?
A)1
B)100
C)1,000
D)100,000
E)1,000,000
6
Which of the following is statements is correct regarding prokaryotic genomes but not eukaryotic genomes?
A)Circular chromosomes can be found within the cell.
B)Linear chromosomes may be found within the cell.
C)Plasmids may be found within the cell
D)Circular and linear chromosomes can be found within the cell.
E)Circular and linear chromosomes can be found within the cell. Plasmids may be found within the cell.
7
True or False: Larger genome sizes do not necessarily correlate to more protein coding genes.
A)True
B)False
8
Arrange the following human DNA sequences in order from largest percentage of the genome to the smallest percentage of the genome.
  1. Exons of protein coding genes
  2. Unique noncoding regions
  3. Introns and enhancers
  4. Repetitive sequences
A)i; ii; iii; iv
B)iii; ii; i; iv
C)ii; iv; i; iii
D)iv; iii; ii; i
E)iv; ii; iii; i
9
Which one of the following statements about transposons is incorrect?
A)Retrotransposons are not found in prokaryotic species.
B)Transposable elements code for an enzyme which facilitates their own movement.
C)Transposition is responsible for much of the repetitive DNA in genomes.
D)Transposable elements can move by a "cut and paste" method but not a "copy and paste" method.
E)Simple transposons are typically flanked by inverted repeat sequences.
10
Paralogs within a species are also referred to as
A)homologs.
B)analogs.
C)pseudogenes.
D)retroelements.
E)orthologs.
11
Which of the following is a goal of the Human Genome Project?
A)Obtain the DNA sequence of the entire human genome.
B)Develop technology for the generation and management of human genome information.
C)Analyze the genomes of model organisms.
D)Develop programs focused on understanding and addressing the ethical, legal and social implications of the results obtained from the Human Genome Project.
E)All of the choices are goals of the Human Genome Project.
12
True or False: The term proteome is most accurately used to describe the entire collection of proteins produced by an organism.
A)True
B)False
13
Which of the following proteins would be the most abundant within a cardiac muscle cell?
A)Collagen, an extracellular matrix protein
B)Myosin, a motor protein
C)Immunoglobulin M, an antibody
D)Phosphofructokinase, a glycolytic enzyme
E)Lactose permease, a transport protein in the lac operon
14
Which of the following proteins would be the)least(abundant within a skeletal muscle cell?
A)Collagen, an extracellular matrix protein
B)Myosin, a motor protein
C)Immunoglobulin M, an antibody
D)Phosphofructokinase, a glycolytic enzyme
E)Lactose permease, a transport protein in the lac operon
15
Which of the following explains why higher eukaryotes are observed to produce more functional proteins than their genomes predict?
A)Post-translational covalent modification
B)Misaligned crossover of homologous chromosomes
C)Alternative splicing
D)Post-translational covalent modification and alternative splicing
E)Post-translational covalent modification, misaligned crossover of homologous chromosomes, and alternative splicing
16
True or False: The genetic characteristics of a single species can be studied and analyzed by creating a genome database.
A)True
B)False
17
When analyzing an unknown DNA sequence to determine the proper amino acid sequence it encodes, researchers may eliminate proposed sequences due to the presence of
A)improper reading frames
B)presence of many stop codons
C)the encoding of a non-functional protein
D)improper reading frames and the presence of many stop codons
E)improper reading frames, presence of many stop codons, and the encoding of a non-functional protein
18
Homologous genes in different species are most accurately referred to as
A)families.
B)convergents.
C)paralogs.
D)orthologs.
E)analogs.
19
Which of the following statements about BLAST is correct?
BLAST
A)is an acronym for basic local assignment search tool.
B)is a computer program which identifies homologous genes within a database.
C)searches must begin with nucleotide sequence data.
D)results typically follow evolutionary relatedness of various species to the target sequence.
E)All of the statements about BLAST are correct.
20
True or False: If a researcher does not already know the function of a gene or encoded protein, bioinformatics is not typically a helpful approach.
A)True
B)False





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