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1
Which of these statements about the lymphatic system is (are) true?
A)In the spleen, reticular cells form a blood-splenic barrier.
B)The thymus is an important filter for lymphatic fluid.
C)The tonsils are areas of diffuse lymphatic tissue that increase in size with age.
D)The spleen filters blood, removing microorganisms and other foreign substances.
E)all of these are true
2
The tonsils that are referred to as "the tonsils" are the
A)lingual tonsils.
B)palatine tonsils.
C)pyloric tonsils.
D)pharyngeal tonsils.
E)splenic tonsils.
3
Which of these is NOT a location for aggregations of lymph nodes?
A)axillary (armpit) region
B)cervical region
C)inguinal (groin) region
D)around the heart
E)around the intestines
4
Lymph nodes
A)contain red and white pulp.
B)have germinal centers where lymphocytes divide.
C)filter the blood.
D)are attached to blood vessels.
E)pump lymph toward the heart.
5
Lymphatic organs
A)contain many neutrophils.
B)may filter blood or lymph.
C)contain dense collagen fibers.
D)include the pancreas and adrenal glands.
E)all of these
6
The spleen
A)has white pulp that is associated with the venous supply.
B)has red pulp that is associated with the arterial supply.
C)filters lymph and puts it back in the blood.
D)acts as a blood reservoir.
E)destroys worn-out lymphocytes.
7
The thymus
A)decreases in size in older adults.
B)produces neutrophils that move to other tissues.
C)responds to foreign substances in the blood.
D)produces a hormone called lymphopathin.
E)all of these
8
With innate immunity,
A)each time the body is exposed to a substance, the response is the same.
B)specificity and memory are involved.
C)the body may become immune to a disease.
D)antibodies may be produced.
E)all of these
9
Which of the following is a protective chemical that lyses cells, found on the surface of cells and in tears and saliva?
A)complement
B)interferon
C)lysozyme
D)mucus
E)sebum
10
A(n) __________ is a group of 20 proteins activated by a series of reactions, in which one activated chemical then activates another; and promotes inflammation, phagocytosis, and cell lysis.
A)complement
B)interferon
C)lysozyme
D)mucus
E)sebum
11
Which of the following is a protein that interferes with virus production, and is produced by most cells in response to a viral infection?
A)complement
B)interferon
C)lysozyme
D)mucus
E)sebum
12
Which of these chemical mediators does NOT promote inflammation?
A)complement
B)histamines
C)leukotrienes
D)interferon
E)prostaglandins
13
The most important phagocytes are
A)lymphocytes and basophils.
B)basophils and mast cells.
C)neutrophils and basophils.
D)neutrophils and macrophages.
E)macrophages and lymphocytes.
14
Neutrophils
A)seldom leave the blood.
B)are usually the last cells to enter infected tissue.
C)enlarge to become macrophages.
D)often die after a single phagocytic episode.
E)all of these
15
Dust cells, microglia, and Kupffer cells are examples of
A)basophils.
B)eosinophils.
C)lymphocytes.
D)macrophages.
E)neutrophils.
16
Natural killer cells
A)are a type of macrophage.
B)exhibit no memory response.
C)recognize cells infected by a specific virus.
D)are produced in the thymus.
E)all of these
17
Which cells release enzymes that break down chemical mediators released by other cells?
A)basophils
B)eosinophils
C)lymphocytes
D)macrophages
E)neutrophils
18
In addition to the symptoms of local inflammation, systemic inflammation results in the
A)production of large numbers of neutrophils from red bone marrow.
B)production of pyrogens.
C)loss of large amounts of fluid from the blood.
D)all of these
19
Which of these results occur in response to the release of chemical mediators?
A)vasodilation
B)chemotactic attraction of phagocytes
C)increased vascular permeability
D)redness and swelling
E)all of these
20
Substances that stimulate adaptive immunity are called
A)antibodies.
B)antigens.
C)pyrogens.
D)chemical mediators.
E)phagocytes.
21
Which of these is an example of a self-antigen?
A)bacterial antigen
B)viral antigen
C)pollen antigen
D)food antigen
E)tumor antigen
22
Antibodies
A)prevent antigens from binding together.
B)promote phagocytosis.
C)inhibit inflammation.
D)block complement activation.
E)prevent breakdown of foreign antigens.
23
An antibody molecule
A)has three polypeptide chains.
B)has both heavy and light chains.
C)has a variable region that can bind to complement.
D)has a constant region that binds to antigens.
E)is the same thing as an MHC molecule.
24
Which antibody accounts for 80-85% of serum antibodies, can cross the placenta, and is responsible for Rh reactions?
A)IgA
B)IgD
C)IgE
D)IgG
E)IgM
25
T cells
A)are processed in the thymus.
B)are responsible for antibody-mediated immunity.
C)originate in the spleen.
D)produce antibodies when activated.
26
The activation of B cells
A)occurs in the process of innate immunity.
B)results in the production of cytotoxic cells.
C)results in the production of antibodies.
D)occurs when macrophages release cytokines.
E)all of these
27
B cells
A)are stimulated by helper T cells.
B)are produced in the thymus.
C)release cytokines.
D)cause cell lysis.
E)all of these
28
The activation of T cells can result in
A)lysis of virus-infected cells.
B)production of memory T cells.
C)production of lymphokines.
D)delayed hypersensitivity reactions.
E)all of these
29
Given these events that are part of helper T cell activation:

1. interleukin-1 released by macrophage (costimulation)
2. antigen processed by macrophage
3. helper T cell binds to macrophage
4. helper T cell releases interleukin-2 and divides
5. antigen displayed on MHC molecule

Arrange the events in the order that they occur as an antigen is recognized and a helper T cell is activated.
A)1,4,2,5,3
B)2,5,3,1,4,
C)3,1,4,2,5
D)4,2,5,3,1
E)5,3,1,4,2
30
MHC molecules are
A)cell-surface glycoproteins that display antigens.
B)proteins found in the mitochondria of a cell.
C)areas of a macrophage that produce interleukin.
D)specific regions of a given antigen that activate a lymphocyte.
E)chemicals produced by helper T cells.
31
MHC class II molecules
A)are found on all cells.
B)are found on antigen-presenting cells.
C)usually display self-antigens.
D)cannot combine with other antigens.
E)both a and c
32
__________ are responsible for the secondary antibody response.
A)Memory B cells
B)Plasma B cells
C)Helper T cells
D)Natural killer cells
33
As the result of a bee sting, Joe B. Hive had an immediate severe reaction, and nearly died. This reaction was caused by
A)B cells.
B)T cells.
C)natural killer cells.
D)macrophages.
E)neutrophils.
34
The antigen-presenting cells that are required for the activation of B cells are
A)B cells.
B)macrophages.
C)dendritic cells.
D)monocytes.
E)mast cells.
35
Interleukins and CD4, B7, and CD28 proteins are all involved in
A)innate immunity.
B)costimulation of helper T cells.
C)suppressing B cell or T cell activity.
D)inflammation.
E)production of T cells in the spleen.
36
B cells are involved in
A)only adaptive immunity.
B)only innate immunity.
C)both adaptive and innate immunity.
37
Neutrophils are involved in
A)only adaptive immunity.
B)only innate immunity.
C)both adaptive and innate immunity.
38
Complement is involved in
A)only adaptive immunity.
B)only innate immunity.
C)both adaptive and innate immunity
39
A vaccination is a way of acquiring
A)passive natural immunity.
B)active natural immunity.
C)active artificial immunity.
D)passive artificial immunity.
40
Antiserum is used to produce
A)active natural immunity.
B)active artificial immunity.
C)passive natural immunity.
D)passive artificial immunity.





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