Chapter 10 Quiz 2

Chapter 10 Quiz 2

Chapter 10 Quiz 2
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1		This is the carbon skeleton for one of the structural isomers of hexane, C₆H₁₄. (All hydrogen atoms and all bonds from carbon atoms to hydrogen atoms have been omitted for clarity.) Which structure is just a different paper-and-pencil representation of the same isomer?
			A)
			B)
			C)
			D)


2		In March 2003, the FDA proposed new rules on dietary supplements. The proposed rules, if adopted, will
			A)	remove ephedra and other potentially dangerous supplements from the market until proven safe.
			B)	bring all dietary supplements under the FDA rules as drugs, rather than as foods.
			C)	establish standards for preventing contamination, and will require better labeling of supplements.
			D)	exempt supplements from testing and record-keeping requirements used by other drugs.


3		Which compound can exist in chiral forms?
			A)
			B)
			C)
			D)


4		What was the original purpose of "anabolic steroids"?
			A)	enable synergistic effects with other drugs
			B)	help patients suffering from wasting illnesses to regain muscle tissue.
			C)	produce a safe and efficient birth control pill
			D)	create a performance enhancing drug for athletes


5		Ibuprofen is generally sold as a racemic mixture. What does that term mean?
			A)	This formulation for ibuprofen is a mixture of structural isomers.
			B)	This formulation for ibuprofen is a mixture of prescription and over-the-counter forms.
			C)	This formulation for ibuprofen is a mixture of compounds with different molecular formulas.
			D)	This formulation for ibuprofen is mixture of optical isomers.


6		This is the structure of the steroid known as
			A)	testosterone.
			B)	androstenedione.
			C)	progesterone.
			D)	cholesterol.


7		Why is it that not all prescription drugs are available as less expensive generic drugs?
			A)	The drug companies are seeking to maximize profits by withholding the exact composition of the brand-name drug to competitors.
			B)	The FDA will not allow generic drugs into the marketplace because of concerns about safety, efficacy, and need.
			C)	It is likely that the drug is about to be reclassified as over-the-counter, making development of a generic form unnecessary.
			D)	The prescribed drug may be a "pioneer" drug and the 20-year patent-protection period may not have expired.


8		Which statement best describes the mechanism of a steroid-based contraceptive?
			A)	Birth-control steroids help stimulate the release of progesterone, essential for implantation of an embryo in uterine cells.
			B)	Birth-control steroids block the formation of estradiol, the female sex hormone, making pregnancy impossible.
			C)	Birth-control steroids mimic the action of progesterone in true pregnancy, which is to inhibit ovulation.
			D)	Birth-control steroids work by releasing norethynodrel from its binding site, allowing ovulation to occur.


9		Organic chemists frequently use the symbol R in chemical formulas. What is the meaning of this symbol?
			A)	R is the symbol for the element rubidium.
			B)	R represents a group of carbon and hydrogen atoms.
			C)	R is used to stand for one or more rings in the compound.
			D)	R indicates the reactive part of the organic molecule.


10		The boxed functional group in this structure is
			A)	an ester.
			B)	a carboxylic acid.
			C)	an amide.
			D)	an ether.


11		This is the condensed structural formula for aspirin, the most widely used drug in the world. What is its molecular formula?
			A)	C₃H₄O₄
			B)	C₈H₈O₄
			C)	C₉H₈O₄
			D)	C₉H₁₀O₄


12		What functional groups and/or important organic linkages are present in this structure for PABA, an active ingredient in many sunscreens?
			A)	amide linkage, ketone group
			B)	organic acid group, ester linkage
			C)	organic acid group, amine group
			D)	alcohol group, peptide linkage


13		Which region of ibuprofen is most responsible for the fact that this drug dissolves well in nonpolar cell membranes and fatty tissues?
			A)	1
			B)	2
			C)	3
			D)	4


14		Which incorrectly pairs a steroid or steroid-like substance with its primary physiological function?
			A)	RU-486, birth control pill (pregnancy preventative)
			B)	cholesterol, cell membrane structural component
			C)	estradiol, female sex hormone
			D)	testosterone, male sex hormone


15		The cyclooxygenase enzyme COX is responsible for the synthesis of hormones, the prostaglandins. Which are not symptoms that result from prostaglandin release in the body?
			A)	fever
			B)	sensitivity to pain
			C)	ability to inhibit bacterial growth
			D)	swelling

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