Biology (Mader), 10th EditionChapter 13:
Regulation of Gene ActivityLearning OutcomesAfter studying this chapter, you should be able to accomplish the following outcomes.
Prokaryotic Regulation
- Define operon, and list its parts.
- Explain how a regulator gene controls transcription of an operon.
- Explain the regulation of the trp and lac operons.
Eukaryotic Regulation
- List the levels at which gene expression in eukaryotes may be regulated.
- Explain how DNA unpacking may be used to activate gene expression.
- Define epigenetic inheritance.
- Name the two types of transcription factors in eukaryotes and describe how they alter gene expression.
- List the different types of posttranscriptional, translational, and posttranslational control of gene expression in eukaryotes.
- Explain how defects in alternative mRNA splicing may cause disease in humans.
Regulation Through Gene Mutations
- Compare and contrast spontaneous and induced mutations.
- Explain how a point mutations or frameshift mutations in a gene may alter the activity of the protein it encodes.
- Describe how the accumulation of mutations in a cell may cause cancer.
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