Biology (Mader), 10th Edition

Chapter 9: The Cell Cycle and Cellular Reproduction

New Cancer Clue

Objective: The student will identify the role of micro RNA genes in the development of various cancers and to examine their potential as a target for therapy.

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1.

Products made from micro RNA genes:
A)bind directly to DNA and alter its replication
B)bind directly to mRNA and alter its expression
C)bind directly to ribosomes and alter their ability to make protein
D)none of the above
2.

Micro RNA genes have been found associated with which human cancers?
A)leukemia
B)lung
C)brain
D)a and b
E)all of the above
3.

In cancer cells, miR-155 appears to:
A)have diminished expression and activity
B)function as a tumor suppressor
C)have enhanced expression and activity
D)all of the above
4.

In developing a treatment based upon targeting micro RNA genes, the scientists:
A)may use antisense RNA to inhibit the activity of overexpressed micro RNA gene products
B)may inject a patient with extra copies of diminished micro RNA gene products
C)may genetically engineer the micro RNA genes using viral vectors
D)a and b
E)all of the above
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