Hole's Human Anatomy & Physiology (Shier), 12th Edition

Learning Outcome 14.2

1			The percentage of blood cells in whole blood is called _____.
			A)	plasma
			B)	hematocrit
			C)	erythrocytes
			D)	serum

Learning Outcome 14.2

2			The buffy coat evidenced by separating blood cells is comprised of _____.
			A)	erythrocytes
			B)	platelets
			C)	white cells
			D)	platelets and leukocytes

Learning Outcome 14.2

3			Which blood components transport most of the gases?
			A)	erythrocytes
			B)	platelets
			C)	leukocytes
			D)	plasma

Learning Outcome 14.2

4			Each red cell contains about _____% of its volume as the pigment hemoglobin.
			A)	5
			B)	10
			C)	33
			D)	66

Learning Outcome 14.7

5			Which of the following is an agranulocyte?
			A)	neutrophil
			B)	monocyte
			C)	basophil
			D)	eosinophil

Learning Outcome 14.4

6			Which condition is characterized by an abnormal increase in red blood cell count?
			A)	polycythemia
			B)	anemia
			C)	leukemia
			D)	porphyria

Learning Outcome 14.4

7			Which condition is caused by a deficiency of vitamin B12?
			A)	aplastic anemia
			B)	pernicious anemia
			C)	hemolytic anemia
			D)	hemorrhagic anemia

Learning Outcome 14.7

8			Which cells are also called polymorphonuclear leukocytes?
			A)	monocytes
			B)	basophils
			C)	lymphocytes
			D)	neutrophils

Learning Outcome 14.7

9			Which cells are the rarest leukocytes?
			A)	monocytes
			B)	basophils
			C)	eosinophils
			D)	lymphocytes

Learning Outcome 14.9

10			Which organ has the greatest role in synthesizing most blood nutrients?
			A)	intestine
			B)	liver
			C)	stomach
			D)	skeletal muscle

Learning Outcome 14.9

11			Which of these is mainly comprised of triglycerides?
			A)	HDL
			B)	LDL
			C)	VLDL
			D)	chylomicron

Learning Outcome 14.9

12			Which of these has the highest proportion of protein?
			A)	chylomicron
			B)	VLDL
			C)	LDL
			D)	HDL

Learning Outcome 14.9

13			Which lipoprotein has the highest percentage of cholesterol?
			A)	VLDL
			B)	LDL
			C)	HDL
			D)	chylomicron

Learning Outcome 14.9

14			During protein catabolism, _____ is produced as an end product by the liver.
			A)	urea
			B)	uric acid
			C)	creatine
			D)	creatinine

Learning Outcome 14.11

15			Which factor promotes the appearance of the platelet plug?
			A)	collagen
			B)	serotonin
			C)	fibrinogen
			D)	vasodilation

Learning Outcome 14.3

16			The precursor of all lines of blood cells is the _______________.
			A)	myeloblast
			B)	hemocytoblast
			C)	proerythroblast
			D)	progranulocyte

Learning Outcome 14.5

17			When red blood cells are worn out, part of their components are recycled while others are disposed. Select the incorrect statement about destruction of red blood cells.
			A)	The greenish pigment, biliverdin, is recycled to the bone marrow.
			B)	Iron is carried to the bone marrow by a protein called transferrin.
			C)	Biliverdin and bilirubin impart color to bile.
			D)	Macrophages in the liver and spleen destroy worn out red blood cells.

Learning Outcome 14.6

18			Which dietary component(s) is/are needed for DNA synthesis, and thus greatly influence the production of red blood cells?
			A)	calcium
			B)	iron
			C)	vitamin B12 and folic acid
			D)	protein

Learning Outcome 14.4

19			The type of anemia that is fairly common and caused by insufficient dietary iron is ______________.
			A)	aplastic anemia
			B)	pernicious anemia
			C)	hemolytic anemia
			D)	iron deficiency anemia

Learning Outcome 14.7

20			The type of white blood cell that is often the first to arrive at the site of infection is a granulocyte and contains granules that stains light purple is a _______________.
			A)	basophil
			B)	eosinophil
			C)	neutrophil
			D)	monocyte

Learning Outcome 14.2

21			Which cell has no nucleus when it is mature?
			A)	platelet
			B)	neutrophil
			C)	erythrocyte
			D)	lymphocyte

Learning Outcome 14.3

22			Which of these factors will increase the RBC or RCC?
			A)	exercise
			B)	dieting
			C)	low body temperature
			D)	decreased altitudes

Learning Outcome 14.3

23			Which of the following does NOT belong with the others?
			A)	heme
			B)	globin
			C)	bilirubin
			D)	biliverdin

Learning Outcome 14.5

24			Which of these is the earliest of this cell line?
			A)	reticulocyte
			B)	erythrocyte
			C)	erythroblast
			D)	hemocytoblast

Learning Outcome 14.5

25			Red blood cells live around _____ before they disintegrate.
			A)	one month
			B)	120 days
			C)	21 days
			D)	three months

Learning Outcome 14.3

26			Which organ has a primary role in stimulating blood cell formation?
			A)	kidney
			B)	liver
			C)	bone marrow
			D)	spleen

Learning Outcome 14.3

27			Which of the following is not a site of red blood cell production in the fetus?
			A)	bone marrow
			B)	kidney
			C)	liver
			D)	spleen

Learning Outcome 14.8

28			Which of the following is a young platelet?
			A)	progranulocyte
			B)	basophilic band cell
			C)	monoblast
			D)	megakaryoblast

Learning Outcome 14.3

29			Which of these did NOT develop from a myeloblast?
			A)	basophil
			B)	monocyte
			C)	eosinophil
			D)	neutrophil

Learning Outcome 14.6

30			Which of the following is least essential for erythrocyte development?
			A)	vitamin B12
			B)	vitamin B6
			C)	folic acid
			D)	gastric intrinsic factor

Learning Outcome 14.7

31			Which white blood cells are the most common?
			A)	leukocytes
			B)	monocytes
			C)	neutrophils
			D)	lymphocytes

Learning Outcome 14.7

32			Which leukocytes are the largest in the peripheral blood?
			A)	monocytes
			B)	lymphocytes
			C)	basophils
			D)	neutrophils

Learning Outcome 14.7

33			Which leukocyte does NOT have phagocytic properties?
			A)	monocyte
			B)	lymphocyte
			C)	neutrophil
			D)	polymorphonuclear leukocyte

Learning Outcome 14.4

34			The condition called _____ is evidenced by a DIFF over 10,000 per cubic mm of whole blood.
			A)	leukemia
			B)	polycythemia
			C)	leukocytosis
			D)	leukopenia

Learning Outcome 14.7

35			Which of the following is a probable cause of leukocytosis?
			A)	mumps
			B)	chickenpox
			C)	influenza
			D)	appendicitis

Learning Outcome 14.7

36			The ability called _____ explains how a white blood cell could be found in the urine.
			A)	phagocytosis
			B)	diapedesis
			C)	ameboid movement
			D)	infection

Learning Outcome 14.7

37			The _____ cells are actively involved with allergies.
			A)	eosinophil
			B)	erythrocyte
			C)	monocyte
			D)	neutrophil

Learning Outcome 14.7

38			The _____ cells are the usual sources of heparin.
			A)	eosinophil
			B)	basophil
			C)	lymphocyte
			D)	monocyte

Learning Outcome 14.7

39			Which cells release antibodies into the circulation?
			A)	monocytes
			B)	neutrophils
			C)	lymphocytes
			D)	basophils

Learning Outcome 14.7

40			What is the most common cancerous condition in children?
			A)	myeloid leukemia
			B)	lymphoid leukemia
			C)	acute lymphoid leukemia
			D)	chronic lymphoid leukemia

Learning Outcome 14.8

41			Megakaryocytes will differentiate into _____.
			A)	monocytes
			B)	lymphocytes
			C)	platelets
			D)	eosinophils

Learning Outcome 14.8

42			What is a normal platelet count?
			A)	1 million per cubic cc
			B)	200,000 per cubic mm
			C)	1 million per cubic mm
			D)	10,000 per cubic mm

Learning Outcome 14.9

43			Which components of whole blood account for clotting?
			A)	erythrocytes
			B)	eosinophils
			C)	platelets
			D)	neutrophils

Learning Outcome 14.8

44			Which components are the source of serotonin which causes smooth muscle cells to contract?
			A)	platelets
			B)	lymphocytes
			C)	monocytes
			D)	basophils

Learning Outcome 14.8

45			What is the most common component in the plasma?
			A)	sodium chloride
			B)	water
			C)	protein
			D)	platelets

Learning Outcome 14.8

46			How much of the plasma is protein?
			A)	10%
			B)	7%
			C)	25%
			D)	92%

Learning Outcome 14.8

47			Which is the most abundant of the plasma proteins?
			A)	alpha globulin
			B)	beta globulin
			C)	albumin
			D)	fibrinogen

Learning Outcome 14.8

48			What is the most significant factor that helps maintain blood osmotic pressure?
			A)	electrolytes
			B)	albumin
			C)	fibrinogen
			D)	globulins

Learning Outcome 14.8

49			Which molecules are the sources of most antibodies?
			A)	alpha globulin
			B)	beta globulin
			C)	albumin
			D)	gamma globulin

Learning Outcome 14.11

50			Which mineral is essential for coagulation to occur?
			A)	Mg2+
			B)	Ca2+
			C)	Na+
			D)	Fe2+

Learning Outcome 14.11

51			Which chemical initiates the extrinsic phase of clotting?
			A)	fibrin
			B)	fibrinogen
			C)	thromboplastin
			D)	prothrombin

Learning Outcome 14.11

52			Which of the following is NOT always present in the blood?
			A)	prothrombin
			B)	fibrinogen
			C)	calcium
			D)	thrombin

Learning Outcome 14.11

53			What converts fibrinogen to fibrin?
			A)	prothrombin
			B)	thrombin
			C)	calcium
			D)	thromboplastin

Learning Outcome 14.11

54			Which is the last molecule to appear in a clotting reaction?
			A)	fibrinogen
			B)	fibrin
			C)	thrombin
			D)	prothrombin

Learning Outcome 14.12

55			Which of these can dissolve a blood clot?
			A)	heparin
			B)	plasminogen
			C)	plasmin
			D)	PDGF

Learning Outcome 14.11

56			Which of these is a procoagulant?
			A)	heparin
			B)	antithrombin
			C)	vitamin K
			D)	prostacyclin

Learning Outcome 14.13

57			Which is the rarest ABO blood type?
			A)	A
			B)	B
			C)	AB
			D)	O

Learning Outcome 14.14

58			Who is at risk for developing a fatal Rh incompatibility?
			A)	any Rh+ fetus
			B)	second Rh- fetus of Rh+ mother
			C)	second Rh+ fetus of Rh- mother
			D)	Rh- mother

Learning Outcome 14.2

59			Select the statement about red blood cells that is incorrect.
			A)	Mature red blood cells lack nuclei.
			B)	Red blood cells contain hemoglobin.
			C)	Deoxyhemoglobin is saturated with oxygen.
			D)	Red blood cells lack mitochondria.

Learning Outcome 14.7

60			The largest cells in the blood that leave the bloodstream to become macrophages are the _______________.
			A)	eosinophils
			B)	monocytes
			C)	basophils
			D)	neutrophils

Learning Outcome 14.7

61			A person with eosinophilia, or greater than normal numbers of eosinophils, is most likely suffering from ____________.
			A)	allergies or internal parasites
			B)	anemia
			C)	an autoimmune disease
			D)	diabetes

Learning Outcome 14.7

62			An acute infection would show up in a blood count as ______________.
			A)	leukopenia
			B)	leukocytosis
			C)	too few helper T cells
			D)	thrombocytopenia

Learning Outcome 14.9

63			Which plasma proteins help transport lipids in the bloodstream?
			A)	albumins
			B)	alpha and beta globulins
			C)	fibrinogen
			D)	gamma globulins

Learning Outcome 14.9

64			Sedentary people with elevated triglyceride levels who continue to eat fatty foods are likely to have high levels of ____________ in their bloodstream.
			A)	high-density lipoprotein (HDL)
			B)	low-density lipoprotein (LDL)
			C)	very-low density lipoprotein (VLDL)
			D)	chylomicrons

Learning Outcome 14.10

65			Choose the correct order for the steps of hemostasis.
			A)	blood coagulation, platelet plug formation, blood vessel spasm
			B)	platelet plug formation, blood coagulation, blood vessel spasm
			C)	blood vessel spasm, platelet plug formation, blood coagulation
			D)	blood vessel spasm, blood coagulation, platelet plug formation

Learning Outcome 14.11

66			Which clotting factor is released from damaged tissue, and initiates a chain of clotting events?
			A)	prothrombin
			B)	thrombin
			C)	fibrin
			D)	tissue thromboplastin

Learning Outcome 14.2

67			Which blood cell can be described as being a biconcave disc?
			A)	platelet
			B)	neutrophil
			C)	eosinophil
			D)	erythrocyte

Learning Outcome 14.2

68			Which of the following does NOT belong with the others?
			A)	erythrocyte
			B)	serum
			C)	leukocyte
			D)	platelet

Learning Outcome 14.1

69			Which of the following directly defines the transportation of oxygen?
			A)	hemoglobin
			B)	oxyhemoglobin
			C)	reduced hemoglobin
			D)	red cell count

Learning Outcome 14.5

70			Red blood cells survive around _____ days.
			A)	120
			B)	240
			C)	10
			D)	360

Learning Outcome 14.7

71			Which of the following indicates a normal white blood cell count?
			A)	1 million per mm3
			B)	15,000 per cm3
			C)	10,000 per mm3
			D)	3,000 per mm3

Learning Outcome 14.7

72			Which of these cell types should NOT be grouped with the others?
			A)	neutrophil
			B)	lymphocyte
			C)	eosinophil
			D)	basophil

Learning Outcome 14.4

73			Which type of condition is directly related to bone marrow suppression?
			A)	aplastic anemia
			B)	anemia
			C)	sickle cell anemia
			D)	megaloblastic anemia

Learning Outcome 14.1

74			Pregnancy requires the addition of supplements containing iron to support the increase in vasculature and oxygen demand.
			A)	True
			B)	False

Learning Outcome 14.4

75			It is possible to have anemia even when the erythrocyte count is above normal.
			A)	True
			B)	False

Learning Outcome 14.7

76			All leukocytes usually live from 7 to 21 days.
			A)	True
			B)	False

Learning Outcome 14.7

77			Lymphocytes contain lysosomes, which actively decompose bacteria they engulf.
			A)	True
			B)	False

Learning Outcome 14.7

78			The red color in inflammation is partially explained by the ability of erythrocytes to secrete histamines.
			A)	True
			B)	False

Learning Outcome 14.7

79			Pus contains living as well as dead leukocytes that were summoned to the area by positive chemotaxis.
			A)	True
			B)	False

Learning Outcome 14.8

80			Thrombocytopenia or an increased tendency to bleed is a common consequence of leukemia.
			A)	True
			B)	False

Learning Outcome 14.7

81			Leukemic cells can be found within the brain or lungs.
			A)	True
			B)	False

Learning Outcome 14.9

82			A drop in osmotic pressure with resulting edema can be caused by a poor diet or liver disease.
			A)	True
			B)	False

Learning Outcome 14.9

83			High density lipoproteins have relatively more lipids than proteins.
			A)	True
			B)	False

Learning Outcome 14.9

84			Familial hypercholesterolemia is a genetic condition which is characterized by high plasma LDL and increased risk of heart attack.
			A)	True
			B)	False

Learning Outcome 14.9

85			Excessive amounts of creatinine in the blood could result from muscle or kidney disorders.
			A)	True
			B)	False

Learning Outcome 14.10

86			Vessel spasm can be an effective method of hemostasis.
			A)	True
			B)	False

Learning Outcome 14.11

87			Damage to tissues initiates the intrinsic phase of clotting.
			A)	True
			B)	False

Learning Outcome 14.10

88			Bleeding is a symptom of disseminated intravascular coagulation (DIC).
			A)	True
			B)	False

Learning Outcome 14.2

89			Serum is the liquid portion of the blood that cannot clot.
			A)	True
			B)	False

Learning Outcome 14.11

90			Streptokinase and urokinase are used to directly dissolve a thrombus that has moved into the lung.
			A)	True
			B)	False

Learning Outcome 14.13

91			Persons with type A agglutinogen will have anti-B agglutinin in their blood also.
			A)	True
			B)	False

Learning Outcome 14.2

92			Plasma is about 45% of the total blood volume.
			A)	True
			B)	False

Learning Outcome 14.6

93			Males have more red blood cells than females.
			A)	True
			B)	False

Learning Outcome 14.1

94			Cyanosis is the blue color of white skin caused by the presence of oxyhemoglobin.
			A)	True
			B)	False

Learning Outcome 14.1

95			Sickle cell anemia is identified by the presence of abnormally shaped red blood cells.
			A)	True
			B)	False

Learning Outcome 14.7

96			All white blood cells retain their nucleus throughout the life of the cell.
			A)	True
			B)	False

Learning Outcome 14.7

97			Monocytes become macrophages as they leave the blood and enter the tissue spaces.
			A)	True
			B)	False

Learning Outcome 14.1

98			It is more likely to find the smaller red blood cells in a urine specimen than the larger leukocytes.
			A)	True
			B)	False

Learning Outcome 14.10

99			Patients with leukemia often suffer clotting abnormalities and internal bleeding.
			A)	True
			B)	False