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| 1 | |
Look at your data. Is there a relationship between the amplitude of the two EPSPs? |
| | A) | If the first EPSP was small the second exhibited facilitation (i.e. EPSP #2 was larger). |
| | B) | If the first EPSP was small the second exhibited depression (i.e. EPSP #2 was smaller). |
| | C) | Pairs of EPSPs were the same size. |
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| 2 | |
Looking at responses that showed synaptic facilitation, where EPSP #2 was larger. Was EPSP #2 produced by secretion of: |
| | A) | fewer synaptic vesicles than EPSP #1. |
| | B) | the same number of synaptic vesicles than EPSP #1. |
| | C) | more synaptic vesicles than EPSP #1. |
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| 3 | |
Synaptic facilitation is produced by a higher concentration of calcium in the terminal during the second response. The calcium concentration is higher because: |
| | A) | more calcium channels are opened by the second presynaptic action potential. |
| | B) | more calcium enters the terminal during the second presynaptic action potential. |
| | C) | some calcium remains in the terminal from the first presynaptic action potential, and this residual calcium adds to the calcium that enters during the second presynaptic action potential. |
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| 4 | |
Calcium enters the terminal to initiate vesicle release and then is slowly removed. If EPSPs were produced at a closer interval there would e more residual calcium, so: |
| | A) | the second action potential would release more vesicles. |
| | B) | the second action potential would release the same number of vesicles. |
| | C) | the second action potential would release fewer vesicles. |
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| 5 | |
Look at your data. Is there a relationship between the amplitude of the two EPSPs? |
| | A) | If the first EPSP was large the second exhibited facilitation (i.e. EPSP #2 was larger). |
| | B) | If the first EPSP was large the second exhibited depression (i.e. EPSP #2 was smaller). |
| | C) | Pairs of EPSPs were the same size. |
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| 6 | |
If all other variables remain constant, when two action potentials enter the synaptic terminal and produce a pair of EPSPs in the muscle fiber, the larger EPSP is produce by the secretion of: |
| | A) | fewer synaptic vesicles. |
| | B) | the same number of synaptic vesicles. |
| | C) | more synaptic vesicles. |
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| 7 | |
In a chemical synapse that exhibits depression, which response is produced by the secretion of more synaptic vesicles? |
| | A) | (the larger) EPSP #1. |
| | B) | (the smaller) EPSP #2. |
| | C) | neither, both EPSPs are produced by the secretion of the same number of vesicles. |
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| 8 | |
Look at your data. When compared with synapses that exhibit facilitation, synapses that show depression have larger EPSP #1 because: |
| | A) | the response is produced by the release of substantially more synaptic vesicles. |
| | B) | the response is produced by the release of about the same number of synaptic vesicles. |
| | C) | the response is produced by the release of substantially fewer synaptic vesicles. |
| | D) | response amplitude is not associated with the number of synaptic vesicles released. |
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| 9 | |
During synaptic depression, the first action potential releases a large number of synaptic vesicles to produce EPSP #1. At this point: |
| | A) | the level of calcium in the terminal is at resting levels. |
| | B) | the number of vesicles available for release is reduced. |
| | C) | calcium channels can not open to allow more calcium into the terminal. |
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| 10 | |
During synaptic depression the second EPSP is smaller than the first because: |
| | A) | the number of vesicles available for release is smaller than for EPSP #1. |
| | B) | there has been insufficient time to replenish the vesicles released to produce EPSP #1. |
| | C) | the level of calcium in the terminal is greater than for EPSP #1, but fewer vesicles are released. |
| | D) | all of the above statements are true. |
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