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1 |  |  __________ accounts for about 40% of the total body weight. |
|  | A) | Extracellular fluid |
|  | B) | Interstitial fluid |
|  | C) | Intracellular fluid |
|  | D) | Plasma |
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2 |  |  Intracellular fluid |
|  | A) | comprises a smaller percentage of body weight than extracellular fluid. |
|  | B) | has a lower concentration of sodium ions than extracellular fluid. |
|  | C) | has a lower concentration of potassium ions than extracellular fluid. |
|  | D) | has a higher concentration of calcium ions than extracellular fluid. |
|  | E) | all of these |
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3 |  |  If the solute concentration in the extracellular fluid decreases, water |
|  | A) | moves into the cells. |
|  | B) | moves out of the cells. |
|  | C) | moves out of the blood. |
|  | D) | will not move. |
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4 |  |  Approximately 90-95% of the osmotic pressure of the extracellular fluid is caused by ______ and the negative ions associated with them. |
|  | A) | Ca2+ ions |
|  | B) | K+ ions |
|  | C) | Mg2+ ions |
|  | D) | Na+ ions |
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5 |  |  In the body, the dominant extracellular cations are |
|  | A) | Ca2+ ions. |
|  | B) | K+ ions. |
|  | C) | Mg2+ ions. |
|  | D) | Na+ ions. |
|  | E) | Cl- ions. |
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6 |  |  Large organic molecules such as proteins are not usually found in the |
|  | A) | interstitial fluid. |
|  | B) | intracellular fluid. |
|  | C) | plasma. |
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7 |  |  Increased blood pressure stimulates the release of |
|  | A) | aldosterone. |
|  | B) | ADH. |
|  | C) | atrial natriuretic hormone. |
|  | D) | renin. |
|  | E) | angiotensin II. |
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8 |  |  The most important regulator of blood osmolality is |
|  | A) | aldosterone. |
|  | B) | ADH. |
|  | C) | atrial natriuretic hormone. |
|  | D) | renin. |
|  | E) | angiotensin II. |
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9 |  |  If blood pressure decreases, blood levels of __________ increase. |
|  | A) | aldosterone |
|  | B) | angiotensin II |
|  | C) | ADH |
|  | D) | renin |
|  | E) | all of these |
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10 |  |  Which ions are most important for establishing the resting membrane potential (RMP)? |
|  | A) | Ca2+ ions |
|  | B) | Cl- ions |
|  | C) | K+ ions |
|  | D) | Mg2+ ions |
|  | E) | Na+ ions |
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11 |  |  __________ plays a major role in regulating the concentration of K+ ions in the extracellular fluid by increasing the rate of K+ ion secretion in the distal tubule and collecting duct. |
|  | A) | Aldosterone |
|  | B) | Angiotensin II |
|  | C) | ADH |
|  | D) | Atrial natriuretic hormone |
|  | E) | Renin |
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12 |  |  Aldosterone secretion from the adrenal cortex is stimulated by angiotensin II and |
|  | A) | elevated blood Na+ ion levels. |
|  | B) | decreased blood Cl- ion levels. |
|  | C) | elevated blood K+ ion levels. |
|  | D) | decreased blood Ca2+ ion levels. |
|  | E) | elevated blood pressure. |
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13 |  |  Parathyroid hormone __________ blood calcium levels and calcitonin __________ blood calcium levels. |
|  | A) | decreases, decreases |
|  | B) | decreases, increases |
|  | C) | increases, decreases |
|  | D) | increases, increases |
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14 |  |  __________ is necessary for the transport of Ca2+ ions across the wall of the intestinal tract. |
|  | A) | Calcitonin |
|  | B) | PTH |
|  | C) | Aldosterone |
|  | D) | Angiotensin II |
|  | E) | Vitamin D |
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15 |  |  Hypocalcemia has which of these symptoms? |
|  | A) | anorexia |
|  | B) | constipation |
|  | C) | fatigue |
|  | D) | muscle spasms |
|  | E) | kidney stones |
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16 |  |  The major mechanism that controls plasma levels of calcium ions is |
|  | A) | the renin-angiotensin-aldosterone mechanism. |
|  | B) | the phosphate transport mechanism in the nephron. |
|  | C) | atrial natriuretic hormone secretion. |
|  | D) | ADH secretion. |
|  | E) | parathyroid hormone secretion. |
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17 |  |  The most abundant negatively charged ion in the extracellular fluid is |
|  | A) | ammonium. |
|  | B) | bicarbonate |
|  | C) | chloride. |
|  | D) | sulfate. |
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18 |  |  Loss of a large volume of sweat results in the body fluids becoming __________ which causes __________ in plasma volume. |
|  | A) | hypertonic, a decrease |
|  | B) | hypertonic, an increase |
|  | C) | isotonic, no change |
|  | D) | hypotonic, a decrease |
|  | E) | hypotonic, an increase |
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19 |  |  Thirst is stimulated by |
|  | A) | increased osmolality of the blood. |
|  | B) | decreased blood volume. |
|  | C) | increased angiotensin II. |
|  | D) | all of these |
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20 |  |  Which of these normally represents the SMALLEST source of water loss from the body? |
|  | A) | evaporation |
|  | B) | feces |
|  | C) | sensible and insensible perspiration |
|  | D) | urine |
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21 |  |  During conditions of severe dehydration, hematocrit __________ , which results in a(n) __________ in blood viscosity. |
|  | A) | decreases, decrease |
|  | B) | decreases, increase |
|  | C) | increases, decrease |
|  | D) | increases, increase |
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22 |  |  The ____________ are the primary organs that regulate the composition and volume of body fluids. |
|  | A) | kidneys |
|  | B) | lungs |
|  | C) | blood vessels |
|  | D) | intestines |
|  | E) | liver and gall bladder |
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23 |  |  Which of these conditions produces a large volume of dilute urine? |
|  | A) | decreased ADH secretion |
|  | B) | increased renin secretion |
|  | C) | increased angiotensin II production |
|  | D) | increased aldosterone secretion |
|  | E) | all of these |
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24 |  |  An acid |
|  | A) | has a pH below 7. |
|  | B) | that completely dissociates in solution is a strong acid. |
|  | C) | releases hydrogen ions into a solution. |
|  | D) | is a compound such as H2CO3. |
|  | E) | all of these |
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25 |  |  Which of these is NOT one of the major buffer systems in the body? |
|  | A) | lactic acid buffer system |
|  | B) | carbonic acid/bicarbonate buffer system |
|  | C) | phosphate buffer system |
|  | D) | protein buffer system |
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26 |  |  Buffers |
|  | A) | bind to excess H+ ions that are added to a solution. |
|  | B) | prevent large changes in body fluid pH. |
|  | C) | may involve weak acids. |
|  | D) | release H+ ions when H+ ion concentration in a solution falls. |
|  | E) | all of these |
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27 |  |  Nephrons directly regulate acid-base balance by |
|  | A) | combining H+ ions with Cl- ions. |
|  | B) | forming carbon dioxide. |
|  | C) | secreting H+ ions into the filtrate. |
|  | D) | producing carbonic anhydrase. |
|  | E) | producing protein buffers. |
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28 |  |  The major effect of acidosis is the __________ of the nervous system, whereas a major effect of alkalosis is __________ of the nervous system. |
|  | A) | depression, hyperexcitability |
|  | B) | hyperexcitability, depression |
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29 |  |  The largest buffer system in the body is the |
|  | A) | carbonic acid/bicarbonate buffer system. |
|  | B) | phosphate buffer system. |
|  | C) | protein buffer system. |
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30 |  |  Respiratory regulation of pH depends upon the |
|  | A) | carbonic acid/bicarbonate buffer system. |
|  | B) | phosphate buffer system. |
|  | C) | protein buffer system. |
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31 |  |  The reaction between CO2 and H2O is catalyzed by |
|  | A) | angiotensin-converting enzyme. |
|  | B) | carbonic anhydrase. |
|  | C) | sodium bicarbonate. |
|  | D) | phosphate. |
|  | E) | carbonic acid. |
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32 |  |  When hydrogen ions are secreted into the lumen of the nephron, sodium ions and __________ pass into the extracellular fluid. |
|  | A) | chloride ions |
|  | B) | potassium ions |
|  | C) | calcium ions |
|  | D) | bicarbonate ions |
|  | E) | sulfate ions |
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33 |  |  Decreased elimination of CO2 from the body causes pH to __________ and can result in __________ . |
|  | A) | decrease, acidosis |
|  | B) | decrease, alkalosis |
|  | C) | increase, acidosis |
|  | D) | increase, alkalosis |
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34 |  |  If the pH of the blood decreases, the pH of the urine will |
|  | A) | decrease. |
|  | B) | increase. |
|  | C) | be unaffected. |
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35 |  |  Increased ammonia in the urine and a continuously elevated respiratory rate indicate |
|  | A) | respiratory acidosis. |
|  | B) | respiratory alkalosis. |
|  | C) | metabolic acidosis. |
|  | D) | metabolic alkalosis. |
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36 |  |  Which of these is NOT a buffer found in the filtrate of the nephron? |
|  | A) | ammonia |
|  | B) | bicarbonate |
|  | C) | phosphate |
|  | D) | protein |
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37 |  |  Alkalosis |
|  | A) | occurs when the pH of the body fluids is less than 7.35. |
|  | B) | can be caused by hyperventilation. |
|  | C) | can occur as a result of anaerobic respiration. |
|  | D) | can result from production of urine that has a high pH. |
|  | E) | all of these |
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38 |  |  Someone who has untreated diabetes mellitus also likely has |
|  | A) | metabolic acidosis. |
|  | B) | respiratory acidosis. |
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39 |  |  Hypersecretion of aldosterone causes |
|  | A) | increased water retention. |
|  | B) | alkalosis. |
|  | C) | high blood sodium levels. |
|  | D) | all of these |
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40 |  |  Because of greatly decreased PO2, traveling to a very high altitude could cause |
|  | A) | metabolic acidosis. |
|  | B) | respiratory acidosis. |
|  | C) | metabolic alkalosis. |
|  | D) | respiratory alkalosis. |
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