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Student Edition
Instructor Edition
Microbiology, 6/e

Lansing M Prescott, Augustana College
John P Harley, Eastern Kentucky University
Donald A Klein, Colorado State University

ISBN: 0072556781
Copyright year: 2005

What's New

Our New Look . . . Design

The interior of Microbiology, sixth edition, has been completely redesigned. Students today are very sensitive to visual presentations and our new design presents information within the framework of a bright, clean, modern-looking environment. We believe this appealing new look will help students move into the content and focus on the important topics. New icons call attention to the numbered main heads, and colorful headings help the students recognize shifts in focus. All of the boxed essays have been organized around five main themes and identified by category (Historical Highlights, Techniques & Applications, Disease, Microbial Diversity & Ecology, and Microbial Tidbits).

And . . . Illustrations

Tied in to this bright new look is our continuing improvement of our art program. New illustrations have been added to most chapters, and many older figures have been revised to improve their usefulness. Particular attention has been paid to consistency in the use of color. We have also tried to employ colors in such a way that the figures are easier to understand.

Not Just a New Look . . . New Content

Due to the fast pace of discoveries in the life sciences, substantial changes and updates have been made to keep the adopters of the sixth edition at the cutting edge of information. A summary of important new material by parts includes:

Parts One-Six (chapters 1-18) introduce the foundations of microbiology: the development of the field, the structure of microorganisms, microbial growth and control, metabolism, molecular biology and genetics, DNA technology and genomics, and the nature of viruses.

New and Significantly Updated Topics
Chapter 3 - Protein secretion in procaryotes; fimbriae and bacterial movement
Chapter 6 - Thermophile survival in high-temperature environments and the effect of salt on microbial growth
Chapter 11 - Antiparallel nature of DNA
Chapter 12 - Atomic structures of RNA polymerase and ribosomes; regulation by sRNA
Chapter 15 - Thoroughly updated information on completed genomes
Chapter 18 - Construction of the poliovirus from its genome sequence; mechanism of prion action; virus entry into host cells

Part Seven, The Diversity of the Microbial World (chapters 19 - 27) contains a survey of the procaryotes that closely follows the general organization of the second edition of Bergey's Manual of Systematic Bacteriology. Although principal attention is devoted to bacteria, the fungi, algae, and protozoa receive more than usual coverage.

New and Significantly Updated Topics
Chapter 19 - Use of signature sequences in phylogenetic analysis; updated discussion of the classification system in the second edition of Bergey's Manual of Systematic Bacteriology
Chapter 20 - Methane-consuming archaea and protein secretion in the archaea

Part Eight, Ecology and Symbiosis (chapters 28 - 30) focuses on the relationships of microorganisms to other organisms and the environment (microbial ecology). Aquatic and terrestrial microbiology are introduced here.

New and Significantly Updated Topics
Chapter 28 - Methods of microbial ecology; discussion of lichens as controlled parasitic relationships; genomic reduction resulting from endosymbiosis; coevolution of gut microorganisms; inclusion of latest information on the hyperthermophile, Geogemma barossii
Chapter 29 - Addition of Cryptosporidium to U.S. drinking water standards; removal of nitrogen and phosphorus by on-site water treatment processes; Canadian geese as a reservoir for Giardia and Cryptosporidium
Chapter 30 - Occurrence of polyprosthecate bacteria such as Verrucomicrobium; the role of the oxidative burst in plant-microbe interactions; mycorrhizal interactions with achlorophyllous plants

Parts Nine and Ten, Nonspecific (Innate) Resistance and the Immune Response; Microbial Diseases and Their Control (chapters 31 - 33 in Part Nine and 34 - 40 in Part Ten) are concerned with pathogenicity, resistance, and disease. The disease survey is organized taxonomically on the chapter level; within each chapter diseases are covered according to mode of transmission. This provides flexibility and allows the student to easily locate information on a disease of interest.

New and Significantly Updated Topics
Chapter 31 - Cathelicidin antimicrobial peptides; pattern-recognition receptors on macrophages, and Toll-like receptors in nonphagocytic host defense
Chapter 33 - Vaccine table includes the latest recommendations approved for use in the United States including five new vaccines
Chapter 34 - Use of actin-based motility by bacterial pathogens to spread within the host
Chapter 35 - The Etest for antibiotic sensitivity; expansion of information on drug inactivation by chemical modification; discussion of antibiotic resistance genes on genetic elements other than plasmids
Chapter 37 - New essays on the first recorded incidence of biological warfare and the SARS epidemic
Chapter 38 - New or expanded discussion of smallpox, West Nile virus, and hepatitis G virus
Chapter 39 - Weaponization of anthrax and expanded information on anthrax

Part Eleven, Food and Industrial Microbiology (chapters 41 - 42) concludes the text with an introduction to these fields.

New and Significantly Updated Topics
Chapter 41 - Norwalk-like viruses in food and water; malo-lactic fermentation in wine production; use of probiotic Lactobacillus in feed to reduce the occurrence of E. coli in beef cattle
Chapter 42 - Discussion of newest approaches for recovery from nature of previously "unculturable" microorganisms

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