1. How are transcription and translation economical?
2. Refer to the figure above to answer the following questions: a. What are the next three amino acids to be added to peptide b?b. Fill in the correct codons in the mRNA opposite the template DNA strand.c. What is the sequence of the DNA coding strand (as much as can be determined from the figure)?d. Is the end of the peptide encoded by this gene indicated in the figure? How can you tell?e. What might happen to peptide b after it is terminated and released from the ribosome?
3. List three mRNA sequences that could encode this amino acid sequence:
4. List the codons of a one-nucleotide genetic code and of a two-nucleotide genetic code. Why are these codes insufficient?
5. Write a DNA sequence that would encode this amino acid sequence:
6. When Crick and his coworkers examined synthetic RNA of sequence ACACACACACACACA… they found that it is the encoded the amino acid sequence for thr-his-thr-his-thr…. What would a next step be in determining the codon assignments for ACA and CAC?
7. How is complementary base pairing responsible for:a. The structure of the DNA double helix?b. DNA replication?c. Transcription of RNA from DNA?d. mRNA’s attachment to a ribosome?e. Codon-anticodon pairing?f. tRNA conformation?
8. What changes does RNA undergo after transcription and a protein undergo after translation?
9. How can a defect in protein folding cause disease?
10. State the sequence of an antisense RNA that might be used to fight a virus that has a partial DNA template sequence of TTCGCTAAAGACTGT.
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