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| 1 | |
Signs and symptoms of inflammation include all the following EXCEPT |
| | A) | redness |
| | B) | heat |
| | C) | cough |
| | D) | edema |
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| 2 | |
"Undesirable immune reactions" include all the following EXCEPT |
| | A) | asthma |
| | B) | rheumatism |
| | C) | hay fever |
| | D) | influenza |
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| 3 | |
There are four categories of hypersensitivity reactions including |
| | A) | Type I — IgG and IgM tissue destruction. |
| | B) | Type II — allergy and anaphylaxis. |
| | C) | Type III — immune complex reactions. |
| | D) | Type IV — reaction to vaccines. |
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| 4 | |
Antigens that trigger hypersensitivity reactions are called |
| | A) | allergens. |
| | B) | overreactive. |
| | C) | immunodeficient. |
| | D) | antibodies. |
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| 5 | |
Immediate hypersensitivity is |
| | A) | IgE-mediated and involves mast cells, basophils, and allergic mediators. |
| | B) | IgG, IgM antibodies acting upon cells with complement and resulting in cell lysis. |
| | C) | antibody-mediated inflammation. |
| | D) | delayed hypersensitivity and results in cytotoxic reactions in tissues. |
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| 6 | |
An example of antibody-mediated hypersensitivity includes |
| | A) | hay fever and asthma. |
| | B) | blood group incompatibility. |
| | C) | rheumatic fever. |
| | D) | graft rejection. |
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| 7 | |
______ is any chronic local allergy such as hay fever or asthma. |
| | A) | Atopy |
| | B) | Anaphylaxis |
| | C) | Eczema |
| | D) | Type II hypersensitivity |
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| 8 | |
Allergens that enter by mouth are called |
| | A) | inhalants. |
| | B) | injectants. |
| | C) | contactants. |
| | D) | ingestants. |
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| 9 | |
Allergic rhinitis is a seasonal reaction to plant pollen or molds and |
| | A) | is an acute condition. |
| | B) | is also called hay fever. |
| | C) | is caused by ingestants. |
| | D) | causes vomiting and nausea. |
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| 10 | |
Type I hypersensitivity reactions |
| | A) | result from excessive IgE production in response to an exogenous antigen. |
| | B) | consist of three types. |
| | C) | tend to be acquired through exposure. |
| | D) | are not generally be influenced by age, geographic locale, or infection. |
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| 11 | |
Systemic anaphylaxis is characterized by |
| | A) | "wheal and flare" reaction. |
| | B) | overreaction at first exposure to antigen. |
| | C) | vomiting and diarrhea. |
| | D) | sudden respiratory and circulatory disruption. |
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| 12 | |
Primary mediators in Type I hypersensitivities include |
| | A) | IgA, IgG, IgM |
| | B) | complement, IgG, IgM |
| | C) | IgE, basophils, mast cells |
| | D) | T lymphocytes |
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| 13 | |
Histamine is the most profuse and fast-acting allergic mediator, it |
| | A) | affects nerve cells primarily. |
| | B) | increases mast cell proliferation. |
| | C) | decreases peristalsis. |
| | D) | stimulates smooth muscle and glands. |
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| 14 | |
Blood typing tests are performed by taking blood samples and mixing with |
| | A) | antibodies against O type blood, then observing agglutination. |
| | B) | complement with antigen, then observing hemolysis. |
| | C) | Rh antibodies with antigen, then observing hemolysis. |
| | D) | antibodies against A or B type antigens, then observing agglutination. |
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| 15 | |
The universal blood donor is |
| | A) | Type A. |
| | B) | Type AB. |
| | C) | Type B. |
| | D) | Type O. |
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| 16 | |
Primary mediators in Type II hypersensitivities include |
| | A) | IgA, IgG, IgM |
| | B) | complement, IgG, IgM |
| | C) | IgE, basophils, mast cells |
| | D) | T lymphocytes |
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| 17 | |
Type III hypersensitivities |
| | A) | are induced when a profuse amount of antibodies enter the system. |
| | B) | result in large quantities of antigen formation. |
| | C) | ultimately form small, insoluble immune complexes that settle in basement membranes. |
| | D) | all of the above. |
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| 18 | |
Primary mediators in Type III hypersensitivities include |
| | A) | IgA, IgG, IgM |
| | B) | complement, IgG, IgM |
| | C) | IgE, basophils, mast cells |
| | D) | T lymphocytes |
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| 19 | |
Primary mediators in Type IV hypersensitivities include |
| | A) | IgA, IgG, IgM |
| | B) | complement, IgG, IgM |
| | C) | IgE, basophils, mast cells |
| | D) | T lymphocytes |
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| 20 | |
Identify the systemic autoimmune disease from the list below. |
| | A) | Graves disease |
| | B) | Pernicious anemia |
| | C) | Type I diabetes |
| | D) | Rheumatoid arthritis |
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| 21 | |
______ explains that during embryonic growth, some tissues are immunologically privileged. |
| | A) | The theory of immune deficiency |
| | B) | Molecular mimicry |
| | C) | The clonal selection theory |
| | D) | The sequestered antigen theory |
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| 22 | |
______ affects skeletal muscle, progressing from weakness to complete loss of muscle function and death, due to autoimmune attack on acetylcholine receptors in nerve transmission. |
| | A) | Myasthenia gravis |
| | B) | Diabetes mellitus |
| | C) | Graves disease |
| | D) | Multiple sclerosis |
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| 23 | |
A(n) _______ is grafting between identical twins. |
| | A) | autograft |
| | B) | isograft |
| | C) | allograft |
| | D) | xenograft |
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| 24 | |
With hemolytic disease of the newborn, the Rh factor is a problem when the mother is _______ and the fetus is ________. |
| | A) | Rh positive; Rh negative |
| | B) | Rh positive; Rh positive |
| | C) | Rh negative; Rh negative |
| | D) | Rh negative; Rh positive |
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| 25 | |
Secondary immunodeficiency is |
| | A) | genetically based. |
| | B) | congenital. |
| | C) | acquired. |
| | D) | gender specific. |
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| 26 | |
Severe Combined Immunodeficiency Syndrome (e.g. the Bubble Boy) is due to |
| | A) | clinical deficiencies in T-cell expression. |
| | B) | abnormal immunoglobulin production. |
| | C) | acquired immunodeficiency. |
| | D) | absence of lymphatic stem cells. |
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| 27 | |
Immunopathology is the study of diseases associated with excesses and deficiencies of the immune system. |
| | A) | True |
| | B) | False |
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| 28 | |
Allergens can be either exogenous and involve the host's own tissue or endogenous and originate outside the host. |
| | A) | True |
| | B) | False |
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| 29 | |
Atopic dermatitis is a skin condition that is intensely itchy and inflammatory and is also known as eczema. |
| | A) | True |
| | B) | False |
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| 30 | |
The best-known infection-induced immunodeficiency is AIDS. |
| | A) | True |
| | B) | False |
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| 31 | |
The “hygiene hypothesis” states that a cleaner environment early in life builds a healthy immune system. |
| | A) | True |
| | B) | False |
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| 32 | |
A blood transfusion reaction is a type II hypersensitivity. |
| | A) | True |
| | B) | False |
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| 33 | |
The Arthus reaction is usually seen after the first round of vaccines at the injection site. |
| | A) | True |
| | B) | False |
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| 34 | |
An allergic reaction to jewelry is a type IV hypersensitivity. |
| | A) | True |
| | B) | False |
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