Site MapHelpFeedbackStudy Outline
Study Outline
(See related pages)

  1. Cytogenetic and Linkage Mapping
    1. Cytogenetic mapping provides a way to determine the locations of genes by microscopically examining the chromosomes
    2. In situ hybridization can localize genes along particular chromosomes
    3. Linkage mapping can use molecular markers
    4. The distance between two linked RFLPs can be determined
    5. An RFLP map describes the locations of many different RFLPs throughout the genome
    6. RFLP analysis can be used to follow the inheritance of disease-causing alleles
    7. Genetic mapping also uses molecular markers called microsatellites
  2. Physical Mapping
    1. Specific chromosomes can be isolated by pulsed-field gel electrophoresis or chromosome sorting
    2. A physical map of a chromosome is constructed by creating a contiguous series of clones from a chromosome-specific library
    3. YAC cloning vectors are used to make contigs of eukaryotic chromosomes
    4. Positional cloning can be achieved using chromosome walking
    5. The Human Genome Project has stimulated genomic research
    6. Many genome sequences have been determined





To learn more about the book this website supports, please visit its Information Center.
(c)2005 McGraw-Hill Higher Education
Any use is subject to the Terms of Use and Privacy Policy.
McGraw-Hill Higher Education is one of the many fine businesses of The McGraw-Hill Companies.


GeneticsOnline Learning Center

Home > Chapter 20 > Study Outline