Biology, Eighth Edition (Raven)

Chapter 14: DNA: The Genetic Material

Learning Outcomes

Chapter 14
  • Describe the experiments that first supported the hypothesis that a cell’s hereditary material is located in the nucleus.
  • Understand the theory and conclusions associated with the Griffith and Avery experiments using Pneumococcus and mice.
  • Explain the evidence that supports the identity of DNA as hereditary material.
  • Identify the three subunits of DNA and describe how they are put together to construct an intact molecule.
  • Understand the importance of Chargaff’s rules and the complementary nature of nucleotide bases.
  • Describe Watson and Crick’s three--dimensional model of DNA based upon Franklin’s X-ray crystallography.
  • Know what is meant by semiconservative replication of DNA and how it was determined.
  • Explain the process of semidiscontinuous replication in both strands of the DNA double helix.
  • Understand the one gene-one polypeptide hypothesis and the experimental evidence behind it.
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