Biology, Eighth Edition (Raven)

Chapter 18: Genomics

Post Test

Imagine an entire chromosome of a creature was cut with several restriction digests to create a series of overlapping fragments (this is impossibly ambitious at this time, but just suppose for now!). These were used to create a giant physical map using restriction mapping techniques. How many contigs would you find when it was completed? (p. 350)
E)It can't be determined from the information given
Human DNA can be stored is a library of (p. 352)
D)a and b only
E)All of the above
Where, within an essential gene, might you most likely find a single-nucleotide polymorphism (SNP)? (p. 358)
A)In the promoter
B)In the template DNA which encodes the start codon
C)In the template DNA which encodes a nucleotide in the wobble position
D)In the coding (nontemplate) strand of DNA which is complementary to the start position of an intron.
E)This is a trick question: you can't have an SNP in an essential gene.
The sequence of an organism's genome has been likened to that of a "parts list" for an organism. How might the proteome be described? (p. 363)
A)It would be like a parts list with instructions for how the pieces are installed.
B)The proteome would represent the suppliers from which the parts are ordered.
C)There is no difference between the genome and proteome: they represent each other very clearly.
D)Proteomics would represent an analysis of the company's history, including all its subsidiaries which contributed to its current-day status.
E)The proteome would represent quantities in which the parts are ordered, and then individually altered to fit a variety of specific activities.
Which of the following is NOT a challenge to the use of genomics for society? (p. 366)
A)Behavioral genomics and its use to diagnose emotional or mental problems early.
B)Individual privacy rights and the need for large amounts of aggregate data in order to spot genetic trends.
C)Use of aggregate data to identify tendency towards disease and the use of these data by insurance companies and employers to improve their actuarial tables.
D)Questions about the ownership of genetic data and how these data can be applied to biotechnology.
E)All of these are challenges for the use of genomics.
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